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Limits of social media monitoring in humaniterian crises
Böhm, Jan ; Šlerka, Josef (advisor) ; Sedláček, Jakub (referee)
Limits of social media monitoring in humanitarian crises This paper explores the use of social network data in humanitarian crises. I introduce three theoretical pillars - the techno-optimist concept of digital humanitarians, which describes how social network data improves the ability of humanitarian organizations to locate people in need of assistance. The second theoretical pillar is an analysis of the use of Facebook and Twitter in the context of the so-called Arab Spring, where I show that each network has specificities that need to be taken into account. I then present the concept of techno- colonialism to show how much of a problem it can be when the use of technology is approached without critical reflection. The theoretical introduction is followed by literature review and my own research. The aim of the literature review is to determine whether the limitations and potential risks of using social network data are perceived by current research. The review shows four main directions that the research addresses - the processing of so- called big crisis data, the analysis of specific tools, the possibilities of crisis management using big data, and critical reflection on the limits of social media monitoring. The literature review concludes by stating that critical reflection on the topic is not...
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Crowdfunding impact on traditional distribution structures
Böhm, Jan ; Zaoral, Ondřej (advisor) ; Šlerka, Josef (referee)
This diploma thesis aims to discover, how crowdfunding influences traditional distributional structures. There are many possibilities, how to approach the problem. I have decided to compare the role of the intermediary in different forms of financing. This means, that by "distributional structures", I understand forms of financing. I compare five forms of financing, that altogether define all important kinds of financial transactions between two subjects: The bilateral model, Crowdfunding, Venture Capital, Market and Banks. As a tool for comparing all the forms, I created "Intermediate chain", that describes the way from one demanding subject, who realises his needs, through finding offering subject, to making and fulfiling a contract. I use the intermediate chain, that analyses this way, to describe all the forms of financing. The outcome of this process is a very detailed description. I describe all the models to verify, how crowdfunding takes over the function of other models. The theoretical frame of the analysis is disintermediation. Only by putting the analysis into this theoretical frame, the whole thesis becomes reasonable: The point is not to describe all the models, how people trade with each other. By the question about the influence of crowdfunding on traditional distributional structures, I...
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Molecular characteristics of ductal carcinoma in situ, and their clinical impact
Böhm, Jan ; Zikán, Michal (advisor) ; Dundr, Pavel (referee) ; Strnad, Pavel (referee)
Objectives: Ductal carcinoma in situ (DCIS) is a non-invasive lesion of an increasing clinical importance. Individual risk assessment is essential for an optimal treatment. Our objective was to identify clinical and molecular characteristics of a subgroup of DCIS with an unfavorable prognosis. Methods: In a population study, we analyzed women with DCIS diagnosed within one mammography screening unit. In the experimental part of this work, we conducted a comparative analysis of five biological markers in normal tissue, DCIS and invasive breast cancer by means of gene expression analysis and analysis of loss of heterozygosity (LOH). Results: We demonstrated a high proportion of pure (no invasive component) DCIS (14.41%) of all breast lesions described as malignant. In our sample, we saw a homogeneous distribution of risk factors without noting a clear pattern identifying high-risk subtypes. We noted significant differences in clinical management of tumors with similar characteristics, which demonstrates the present state of limited use of clinical predictors. In the laboratory experiment, we showed differences in loss of heterozygosity (LOH) between DCIS and invasive breast cancer for BRCA1 (8.69% vs. 44.74%) and BRCA2 (9.52% vs. 45.0%). In contrast, we did not find any differences for p53 (31.82%...
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Molecular characteristics of ductal carcinoma in situ, and their clinical impact
Böhm, Jan ; Zikán, Michal (advisor) ; Dundr, Pavel (referee) ; Strnad, Pavel (referee)
Objectives: Ductal carcinoma in situ (DCIS) is a non-invasive lesion of an increasing clinical importance. Individual risk assessment is essential for an optimal treatment. Our objective was to identify clinical and molecular characteristics of a subgroup of DCIS with an unfavorable prognosis. Methods: In a population study, we analyzed women with DCIS diagnosed within one mammography screening unit. In the experimental part of this work, we conducted a comparative analysis of five biological markers in normal tissue, DCIS and invasive breast cancer by means of gene expression analysis and analysis of loss of heterozygosity (LOH). Results: We demonstrated a high proportion of pure (no invasive component) DCIS (14.41%) of all breast lesions described as malignant. In our sample, we saw a homogeneous distribution of risk factors without noting a clear pattern identifying high-risk subtypes. We noted significant differences in clinical management of tumors with similar characteristics, which demonstrates the present state of limited use of clinical predictors. In the laboratory experiment, we showed differences in loss of heterozygosity (LOH) between DCIS and invasive breast cancer for BRCA1 (8.69% vs. 44.74%) and BRCA2 (9.52% vs. 45.0%). In contrast, we did not find any differences for p53 (31.82%...
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Crowdfunding impact on traditional distribution structures
Böhm, Jan ; Zaoral, Ondřej (advisor) ; Šlerka, Josef (referee)
The main topic of this diploma thesis is the capital allocation. I focus on crowdfunding and study how the development of crowdfunding during the last years influenced options and effectiveness of the capital allocation. I compare crowdfunding with other distributional models. Under the term of "distributional models", I understand funding models, namely bilateral model, banks, stock markets and venture capital. I choose start-ups or arising projects as a medium of exploration. The hypothesis of this thesis is as follows: "Crowdfunding is better model for funding arising projects than venture capital, banks, stock market or bilateral model." To answer the main hypothesis, I analyze two supporting hypothesis. The first hypothesis studies the principle of crowdfunding. It says, that crowdfunding is able to recognize funding-worthy projects better than other models. I want to know, what makes crowdfunding an innovative concept, I study, how the new media manifest themself in the concept of crowdfunding. I analyze, how crowdfunding eliminates individual errors by using the "crowd". And above all, I study how each model addresses the role of an intermediary in the relation between surplus and scarce subjects. The second hypothesis observes, whether crowdfunding provides more money to the arising projects than...
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Crowdfunding impact on traditional distribution structures
Böhm, Jan ; Zaoral, Ondřej (advisor) ; Šlerka, Josef (referee)
This diploma thesis aims to discover, how crowdfunding influences traditional distributional structures. There are many possibilities, how to approach the problem. I have decided to compare the role of the intermediary in different forms of financing. This means, that by "distributional structures", I understand forms of financing. I compare five forms of financing, that altogether define all important kinds of financial transactions between two subjects: The bilateral model, Crowdfunding, Venture Capital, Market and Banks. As a tool for comparing all the forms, I created "Intermediate chain", that describes the way from one demanding subject, who realises his needs, through finding offering subject, to making and fulfiling a contract. I use the intermediate chain, that analyses this way, to describe all the forms of financing. The outcome of this process is a very detailed description. I describe all the models to verify, how crowdfunding takes over the function of other models. The theoretical frame of the analysis is disintermediation. Only by putting the analysis into this theoretical frame, the whole thesis becomes reasonable: The point is not to describe all the models, how people trade with each other. By the question about the influence of crowdfunding on traditional distributional structures, I...
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