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National Repository of Grey Literature 4 records found  Search took 0.00 seconds. 
Protective effect of E. coli strain Nissle 1917 and E. coli strain O83 on the development of inflammation in dextran sulphate sodium-induced colitis in mice
 Hudcovic, Tomáš ; Štěpánková, Renata ; Hrnčíř, Tomáš ; Kozáková, Hana ; Schwarzer, Martin ; Tlaskalová, Helena
The study was focused on the evaluation of probiotic bacteria E. coli strain Nissle 1917 and E. coli strain O83 and their role in the development of intestinal inflammation in DSS model of ulcerative colitis and the route of the application. Intragastrically tubing SCID mice ( with severe combined immunodeficiency) had heavy chages (inflammation) of the colon – part descendens. Intrarectally application had a protective effect on the development of intestinal inflammation – part colon descendens. Proinflammatory cytokines TNF – alpha and IL – 6 were reduce markedly in fragment culture from colon - descendens
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Vliv střevních bakterií na vývoj kolitidy u SCID myší po přenosu CD4+CD45RB high T buněk a na změny těsných spojů (TJs) a Panetových buněk
 Štěpánková, Renata ; Powrie, F. ; Kofroňová, Olga ; Kozáková, Hana ; Hudcovic, Tomáš ; Hrnčíř, Tomáš ; Tlaskalová, Helena
In the model of colitis developing in T cell reconstituted SCID mice pronounced morphological impairment of colon, was accompanied by structural changes of tight junctions and decreased expression of alpha defensins in terminal ileum
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Role segmentované filamentozní bakterie (SFB) u experimentální kolitidy vyvolané u SCID myší rekonstituovaným přenosem CD4+CD45RB/hi T lymfocyty
 Štěpánková, Renata ; Tlaskalová, Helena ; Powrie, F. ; Kozáková, Hana ; Hudcovic, Tomáš
Colitis was present only in conventional SCID mice and mice colonized with defined cocktail microflora plus segmented filamentous bacteria (SFB). Altered tight junctions (TJs) structure was detect histochemically in colitic mice using antibodies against ZO-1 proteins. Structural changes of TJs was important feature of intestinal inflammation
Detailed record
Role segmentované filamentozní bakterie (SFB) u experimentální kolitidy vyvolané u SCID myší rekonstituovaným přenosem CD4+CD45RB/hi T lymfocyty
 Štěpánková, Renata ; Tlaskalová, Helena ; Powrie, F. ; Kozáková, Hana ; Hudcovic, Tomáš ; Kofroňová, Olga
Colitis was present only in conventional SCID mice and mice colonized with defined cocktail microflora plus segmented filamentous bacteria (SFB). Altered tight junctions (TJs) structure was detect histochemically in colitic mice using antibodies against ZO-1 proteins. Structural changes of TJs was important feature of intestinal inflammation
Detailed record

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