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Complications of central venous catheters applications 2011 CDC guedelines
Šťastná, Monika ; Michálek, Pavel (advisor) ; Hocková, Jana (referee)
In the presented diploma thesis I deal with the issue of proper insertion of short-term central venous catheters, adherence to procedures by medical and non-medical staff according to CDC guidelines 2011 during insertion and subsequent treatment in intensive care in a faculty-type medical facility. The aim of the diploma thesis is to determine the occurrence of complications, especially infectious, the level of adherence to recommended procedures in practice according to 2011 CDC guidelines, central venous catheter manipulation, comparison of real activities with recommendations and mapping the level of knowledge of non-medical staff about short-term central venous catheters. The theoretical part deals with the importance of clinical guidelines, central venous catheter in general, complications associated with the central venous catheter and prevention of infectious complications of invasive inputs. For the empirical part of the diploma thesis, a prospective non- randomized observational study of cannulation and possible complications associated with a short- term central venous catheter according to CDC 2011 guidelines was chosen to determine real procedures for insertion, treatment and removal of a short-term central venous catheter. This was supplemented by an exploratory questionnaire survey of...
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Změny ve financování pěstounské péče v ČR
Šťastná, Monika
Šťastná M., Changes in funding for Foster care. Bachelor thesis. Brno: Mendel University, 2016. Bachelor thesis deals with funding for foster care. Primarily with changes, which happened in this field in 2013, because of the amendment to the law on social and legal protection of children. Theoretical part of the thesis contains definitions of the foster care, financing of this system and amendment to the Act. Practical part of the thesis states statistic numbers for foster care and also own work. Results compare two types of foster care, their financing and compare for which of these two types were the amendment economical preferable.
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The role of the Msx1 transcription factor in the intestinal epithelia and colorectal cancer
Šťastná, Monika ; Kořínek, Vladimír (advisor) ; Pergner, Jiří (referee) ; Doubravská, Lenka (referee)
The Wnt signaling pathway represents the principal evolutionarily conserved signaling cascade found in all multicellular organisms. It plays a key role not only in many processes during embryogenesis, but also in maintaining tissue homeostasis and regeneration. By contrast, mutations in genes encoding components of the pathway often result in increased activation of Wnt signaling and underlie onset of many human diseases, particularly cancer. The canonical Wnt signaling pathway is essential for proliferation and maintenance of the pluripotent state of intestinal stem cells and thus for homeostatic renewal of the intestinal epithelium. However, aberrant (hyper)activation of the Wnt signaling pathway is the initial step in development of intestinal neoplasia. Understanding the causes and identifying the consequences of the Wnt signaling hyperactivation is crucial for deciphering mechanisms leading to malignant transformation. Although the canonical Wnt signaling pathway has been the subject of scientific studies for several decades, all regulatory mechanisms and consequences of its hyperactivation have not been completely elucidated yet. During my PhD studies, I focused on understanding function(s) of some components and target genes of this signaling cascade. In this theses, results of my first...
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The Development of the Czech Economy in Conditions of Financial Crisis
Šťastná, Monika ; Svoboda, Roman (advisor) ; Michal, Michal (referee)
This thesis deals with the financial crisis and specifically analyze the impact on the Czech economy. The work is divided into two parts - theoretical part and self analysis. Each part is divided further into two parts. The first part deals with the theory of macroeconomic indicators that describe the performance of the national economy. Described here is the gross domestic product, inflation, employment and unemployment, further indebtedness, foreign trade and balance of payments. The second part deals with the theory of the business cycle, its different types and phases. The end of the theoretical part is devoted to the definition of the word crisis, its historical development and, ultimately, the notion of financial crisis. Own part of the thesis is dedicated to the financial crisis that hit the world in 2008. The first half own work is concerned with the emergence of the crisis in the United States and its gradual relocation to Europe The second part is devoted to the economy of the Czech Republic. Individual performance indicators of the national economy are analyzed in detail and to better illustrate the use of graphs and tables.
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