National Repository of Grey Literature 21 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
The detached house with surgery in Olomouc
Čermák, Pavel ; Vlach, František (referee) ; Štěpánek, Ladislav (advisor)
The theme of the bachelor´s thesis are a design and mainly a project documentation of a detached house with two doping untils and surgery in Olomouc. The building consists of three aboveground floors and basement. The house has a garage for two apartments. Beside the own project documentation an architectual study, fire report and thermal technical assessment.
Automorphing of the Image Pairs
Čermák, Pavel ; Nečas, Ondřej (referee) ; Beran, Vítězslav (advisor)
This thesis I deal with creating automorphing between source and destination image. The thesis describes existing methods and algorithms for creating morphing. The thesis focuses on the design and implementation methods for creating automorphing. For this purpose it is necessary to detect significant points in the image, find correspondence of to these points and create your own morphing.
System for Management of Photographic Collections
Čermák, Pavel ; Juránková, Markéta (referee) ; Zemčík, Pavel (advisor)
This thesis deals with the management of digital photos by metadata contained in the photos. The thesis describes the structure of the formats JFIF, TIFF, RAW and EXIF format for storing metadata into photos. In the next part of this thesis is described the design and implementation of a simple photo management application. The main functionality of the application is focused on bulk editing EXIF metadata in the photos. In the conclusion of this thesis there's a proof of results and discussion about further extension options.
Antimicrobial efficacy of quaternary ammonium salts
Hympánová, Michaela ; Marek, Jan (advisor) ; Pejchalová, Marcela (referee) ; Čermák, Pavel (referee)
This dissertation thesis deals with the antimicrobial susceptibility testing of newly prepared compounds based on quaternary ammonium salts (KAS) and their reference standards commonly used in practice. The new compounds were prepared in cooperation with the Department of Toxicology and Military Pharmacy of the Faculty of Military Health Sciences of the University of Defence and the Biomedical Research Centre at the University Hospital Hradec Králové as a part of joint projects. The antimicrobial activity was established on gram-positive (G+) and gram-negative (G-) bacteria from type culture collections and clinical isolates, in planktonic and biofilm form. At first, the basic antimicrobial activity evaluation was performed by using the microdilution broth method. Additionally, the modified methodology was used to explore the influence of culture broth and initial bacterial density on evaluating the antimicrobial activity. Secondly, by using the quantitative suspension test, that better simulates normal practice conditions, has been successfully implemented at the department for the detailed antimicrobial activity evaluation. Thirdly, the biofilm model based on the Calgary Biofilm Device was successfully introduced and optimized for antibiofilm activity testing. Detailed antibiofilm activity was...
Rozpoznávání drah částic v pixelovém detektoru typu Timepix
Čermák, Jakub ; Čermák, Pavel (advisor) ; Doležal, Zdeněk (referee)
In current particle physics field, the progressive detection technologies are used. The pixel detectors are one of them. These detectors are divided into small subdetectors (pixels), which allow viewing exact tracks of the detected particles. This thesis defines criteria for mathematical description of the shape of the particle tracks of different kinds (e-, γ, p, α, μ) and compares several methods used for a classification -neural networks, decision trees and others. The Pixa software was implemented to process the data measured by pixel detectors. This software implements the characteristics and classification methods and creates statistical and other physical results.
Preparation and photophysical evaluation of tetra-3,4-pyridoporphyrazines suitable for the photodynamic therapy
Čermák, Pavel ; Nováková, Veronika (advisor) ; Roh, Jaroslav (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department: Department of Biophysics and Physical Chemistry Candidate: Pavel Cermak Supervisor: Assoc. Prof. Veronika Novakova, PhD. Title of Thesis: Preparation and photophysical evaluation of tetra-3,4- pyridoporphyrazines suitable for the photodynamic therapy Tetra-3,4-pyridoporphyrazines (TPyPz) are aza-analogues of phthalocyanines. Their large system of conjugated bonds enables them to absorb light in the red part of the absorption spectrum. Due to their ability to produce singlet oxygen, they can be potentially used as photosensitizers in photodynamic therapy (PDT). Its mechanism is based on co-functioning of three elements - photosensitizer, light and oxygen. Photosensitizer excited by light absorption transfers its energy into tissue oxygen, thus, creating cytotoxic singlet oxygen. This method is beneficial for its high selectivity, low toxicity, minimal invasion and fast effect. The aim of this work was to synthetize and study water-soluble TPyPz suitable for PDT. Water solubility was achieved by quarternized amines, forming of salts or using suitable delivery systems (hydrophilic emulsion). Hydrophilicity was also increased by introduction of hydrophilic non-charged substituents (OH). At first, appropriate precursors for...
Clostridium difficile: Molecular typing of clinically significant isolates
Krůtová, Marcela ; Nyč, Otakar (advisor) ; Čermák, Pavel (referee) ; Krásný, Libor (referee)
Currently, Clostridium difficile is a leading nosocomial pathogen due to the spread of epidemic strains. Molecular typing of clinical isolates is an important part of C. difficile occurrence and spread control in hospitals as well as in the community. A total of 2201 clinical C. difficile isolates from 32 hospitals cultured between 2013-2015 were characterized by PCR ribotyping and toxin gene multiplex PCR. A total of 166 different ribotyping profiles were identified, of which 53 ribotyping profiles were represented by at least two isolates for each profile. The most frequently found ribotypes were 176 (n=588, 26.7%) and 001 (n=456, 20.7%) followed by 014 (n=176, 8%), 012 (n=127, 5.8%), 017 (n=85, 3.9%) and 020 (n=68, 3.1%). Out of 2201 isolates, 2024 (92%) isolates were toxigenic and carried genes for toxin A and B, and of these, 677 (33.5%) also carried genes for binary toxin. The remaining 177 (8%) isolates were non-toxigenic. Subtyping of C. difficile isolates using a multilocus variable-number tandem repeats analysis (MLVA), that compared the sum of tandem repeats differences, was performed in C. difficile isolates of ribotype 176 (n=225, 17 hospitals) and in C. difficile isolates of ribotype 001 (n=184, 14 hospitals) cultured in 2014. The clonal relatedness in C. difficile isolates belonging...
Molecular-epidemiological analysis of Mycobacterium tuberculosis strains isolated in the West-Bohemian Region of the Czech Republic including detailed characterisation of anti-tuberculosis drugs-resistant strains
Amlerová, Jana ; Hrabák, Jaroslav (advisor) ; Čermák, Pavel (referee) ; Růžička, Filip (referee)
Molecular-epidemiological analysis of Mycobacterium tuberculosis strains isolated in the West-Bohemian Region of the Czech Republic including detailed characterisation of anti-tuberculosis drugs - resistant strains MUDr. Jana Amlerová Abstract Tuberculosis is contagious infectious disease that embodies significant epidemiological and clinical problem worldwide. Tuberculosis incidence differs considerably in various regions of the world but even the countries with low incidence engage strongly in epidemiology of tuberculosis. Tuberculosis belongs to one of the priorities of WHO, cooperation in this matter takes place on a global scale. Tuberculosis is a social illness; accordingly, the countries with high occurrence of tuberculosis are classified as developing countries. Mainly in Africa, there is the situation being complicated by coexistence of HIV. Generally, Europe represents a region with low incidence of tuberculosis. The Czech Republic is a country with the lowest incidence in the world with less than five new cases per 100 000 inhabitants every year. This situation is among others result of high-level tuberculosis surveillance and effective application of epidemiological arrangements based in legislation. This dissertation thesis examines several fields of tuberculosis, mainly focused on modern...
The methodology proposes criteria for determination of the content of micro-nutrients in soils and their evaluation via useing of the extraction method Mehlich 3: certified methodology for practice
Čermák, Pavel ; Mühlbachová, Gabriela ; Káš, Martin ; Vavera, Radek ; Pechová, Miroslava
The methodology proposes criteria for determination of the content of micro-nutrients in soils and their evaluation via useing of the extraction method Mehlich 3. Extraction procedure Mehlich 3 is the official analytical method currently used in testing system of agricultural soils for the determination of the content of available P, K, Mg and Ca. There are criteria for valuation of content of these available nutrients - see Decree No. 275/1998 Coll., on Agrochemical Testing of Agricultural Soil and Land Surveys of Forest Lands, as amended). The existing criteria for above mentioned nutrients are due to this methodology extended by next five elements (Cu, Fe, Mn, Zn and B), marked in field of plant nutrition as micro-nutrients. The simple and easy Mehlich 3 analytical procedure applicable to a variety of different elements, is already used in a wide range of laboratories, allows to extend the criteria for the others elements. In addition, many laboratories can use the multi-elementar analytical instruments ICP-OES. Suggested criteria will also serve for farmers for valuation of soil supply by micro-elements.
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Preparation and photophysical evaluation of tetra-3,4-pyridoporphyrazines suitable for the photodynamic therapy
Čermák, Pavel ; Nováková, Veronika (advisor) ; Roh, Jaroslav (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department: Department of Biophysics and Physical Chemistry Candidate: Pavel Cermak Supervisor: Assoc. Prof. Veronika Novakova, PhD. Title of Thesis: Preparation and photophysical evaluation of tetra-3,4- pyridoporphyrazines suitable for the photodynamic therapy Tetra-3,4-pyridoporphyrazines (TPyPz) are aza-analogues of phthalocyanines. Their large system of conjugated bonds enables them to absorb light in the red part of the absorption spectrum. Due to their ability to produce singlet oxygen, they can be potentially used as photosensitizers in photodynamic therapy (PDT). Its mechanism is based on co-functioning of three elements - photosensitizer, light and oxygen. Photosensitizer excited by light absorption transfers its energy into tissue oxygen, thus, creating cytotoxic singlet oxygen. This method is beneficial for its high selectivity, low toxicity, minimal invasion and fast effect. The aim of this work was to synthetize and study water-soluble TPyPz suitable for PDT. Water solubility was achieved by quarternized amines, forming of salts or using suitable delivery systems (hydrophilic emulsion). Hydrophilicity was also increased by introduction of hydrophilic non-charged substituents (OH). At first, appropriate precursors for...

National Repository of Grey Literature : 21 records found   1 - 10nextend  jump to record:
See also: similar author names
17 ČERMÁK, Pavel
39 ČERMÁK, Petr
1 Čermák, Patrik
5 Čermák, Peter
39 Čermák, Petr
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