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Generation of NPS for Exposure Experiments from Copper Acetylacetone.
Moravec, Pavel ; Schwarz, Jaroslav ; Vodička, Petr ; Kupčík, Jaroslav ; Švehla, Jaroslav
Particles containing copper are emitted from smelters, iron foundries, power stations, and municipal incinerators (WHO, 1998) and also from brake linings during breaking, Kukutschová et al. (2011). Nanoparticles (NPs) of copper are ingredients in polymers, inks, and bioactive coatings inhibiting the growth of microorganisms, Cioffi at al. (2005), and CuO NPs has been used in antimicrobial textiles, Gabbay and Borkow (2006), therefore they can be easily inhaled. Even though CuO NPs were found highly toxic, Karlsson et al. (2008), in vivo studies of their toxicity are still rather rare. In this work we tested a method of long lasting nanoparticle generation from copper\nacetylacetonate (CuAA) for use in follow up exposure experiments with laboratory animals. The exposure chamber for inhalation experiments was constructed in the\nInstitute of Analytical Chemistry AS CR (Večeřa et al., 2011) and some methods of NPs generation for these experiments were already tested in our laboratory (Moravec et al., 2015, Moravec et al., 2016).
Fulltext: content.csg -  PDF
Plný tet: SKMBT_C22016102412242 - PDF
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Single particle analysis of size-segregated aerosol in Prague city center
Marvanová, S. ; Skoupý, Radim ; Kulich, P. ; Bendl, J. ; Hovorka, J. ; Machala, M.
Particulate matter (PM) is omnipresent pollutant in the ambient air known to cause cardiovascular and respiratory diseases (WHO 2004). Recently, outdoor air pollution and particulate matter in outdoor air pollution were classified as carcinogenic to humans, Group 1 (IARC 2015). Especially, ambient PM of aerodynamic diameter < 100 nm, ultrafine particles, appears to be of great importance due to its high specific surface area and high number concentration (Hughes et al. 1998). Ultrafine particles also easily enter and are being transferred in organisms, and interact with cells and subcellular components (Oberdorster et al. 2005). As the evidence of ultrafine PM significance increased, size-fractionated PMs sampled by various cascade impactors have been employed into the toxicological studies on cell cultures or isolated cells, using the organic extracts of size-fractionated PMs (Topinka et al. 2013, Topinka et al. 2015) or directly the size-fractionated particles (Becker et al. 2003, Ramgolam et al. 2009, Reibman et al. 2002, Loxham et al. 2013, Jalava et al. 2006, Thomson et al. 2015, Jalava et al. 2015). The aim of this study was to evaluate shape and composition of size-segregated aerosol particles, sampled by high volume cascade impactor, using electron microscopy and energy dispersive X-ray spectroscopy (EDX).
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Research Infrastructure ACTRIS-CZ.
Holubová Šmejkalová, A. ; Ždímal, Vladimír ; Váňa, M. ; Klánová, J. ; Dvorská, Alice
Research infrastructure ACTRIS-CZ was adopted on the Czech national roadmap of reaserch infrastructures in 2016. Its coreforms a co-located station Košetice-Křešín u Pacova and special equipment from collaborating partner institutions. Research infrastructure ACTRIS-CZ is focused on atmospheric research, especially on atmospheric aerosol, reactive gases and meteorological parameters.
Fulltext: content.csg - PDF
Plný tet: SKMBT_C22016111512070 - PDF
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