National Repository of Grey Literature 4 records found  Search took 0.00 seconds. 
Novel phthalocyanine photosensitizers for photodynamic therapy of tumorous diseases
Zvolánková, Kateřina ; Macháček, Miloslav (advisor) ; Jirkovská, Anna (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Kateřina Zvolánková Supervisor: Mgr. Miloslav Macháček Title of diploma thesis: Novel phthalocyanine photosensitizers for photodynamic therapy of tumorous diseases Oncological diseases are considered to be a serious global problem for many years. One of the most significant factors of their expansion in human population is an increasing life expectancy. Higher incidence of physical and chemical carcinogens and better diagnostic methods of malignant neoplasms are farther possible factors. According to World Health Organisation (WHO) almost 8 million people in the world die from oncological disease every year, whereas 1.7 million of them are Europeans. Malign tumours in Czech Republic, as well as in the world, are the second most frequent causes of death right after cardiovascular diseases, in both genders. Despite increasing incidence of malign tumours in the world, the mortality rate is decreasing. This decline is connected especially with higher quality of medical care together with availability of new diagnostic and therapeutic means. Thus the therapy of cancer is an important subject of biomedical research. Scientists have been trying to discover an effective and highly selective...
Improvement of company processes to assure safety of products
Zvolánková, Kateřina ; Jankových, Róbert (referee) ; Prostredník, Daniel (advisor)
The diploma thesis devotes to the process of ensuring functional safety of products in Bosch Rexroth Brno, which deals with industrial hydraulic systems. The first part introduces the basic legislative regulations concerning product safety and describes selected standards relevant to this thesis. The second part focuses on Bosch Rexroth and the current state in the field of ensuring functional safety of their products. It also includes a description of the functional safety solution of a specific project – a hydraulic try-out press. At the end of the thesis, improvements to the process of ensuring functional safety in response to the identified shortcomings are proposed.
Countinuous Improvement Process Deployment in sales, service and manufacturing company
Zvolánková, Kateřina ; Krbalová, Maria (referee) ; Blecha, Petr (advisor)
This bachelor’s thesis deals with a continuous improvement process in sales, service and manufacturing in company Bosch Rexroth Brno. The goal is to propose the improvement of mentioned processes. First part is devoted to a description of the actual situation and tools used to realize a continuous improvement. That includes an evaluation of their positives and negatives. Second part is focused on a proposal and a description of tools, which respond to important negative findings. Chosen tools are implemented into the continuous improvement process.
Novel phthalocyanine photosensitizers for photodynamic therapy of tumorous diseases
Zvolánková, Kateřina ; Macháček, Miloslav (advisor) ; Jirkovská, Anna (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Kateřina Zvolánková Supervisor: Mgr. Miloslav Macháček Title of diploma thesis: Novel phthalocyanine photosensitizers for photodynamic therapy of tumorous diseases Oncological diseases are considered to be a serious global problem for many years. One of the most significant factors of their expansion in human population is an increasing life expectancy. Higher incidence of physical and chemical carcinogens and better diagnostic methods of malignant neoplasms are farther possible factors. According to World Health Organisation (WHO) almost 8 million people in the world die from oncological disease every year, whereas 1.7 million of them are Europeans. Malign tumours in Czech Republic, as well as in the world, are the second most frequent causes of death right after cardiovascular diseases, in both genders. Despite increasing incidence of malign tumours in the world, the mortality rate is decreasing. This decline is connected especially with higher quality of medical care together with availability of new diagnostic and therapeutic means. Thus the therapy of cancer is an important subject of biomedical research. Scientists have been trying to discover an effective and highly selective...

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