|
|
Alcaloids: Structural analysis employing NMR spectroscopy
Mizerová, Veronika ; Kuneš, Jiří (advisor) ; Špulák, Marcel (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Organic And Bioorganic Chemistry Candidate: Veronika Mizerová Supervisor: doc. PharmDr. Jiří Kuneš, CSc. Title of Thesis: Alcaloids: Structural analysis employing NMR spectroscopy Keywords: NMR spectroscopy, analysis of spectrum, alcaloids This diploma thesis is devoted to the problematics of the structure detecting of unknown substances via nuclear magnetic resonance. In the theoretical part the thesis generally summarizes the characteristics of the plants, which were the substances isolated from. This case concerns alkaloids, that were isolated at the Department of Pharmaceutical Botany and Ecology from the plants called Papaver Rhoeas from the family of Papaveraceae and Narcissus cv. PROFESSOR EINSTEIN from the family of Amaryllidaceae. In the experimental part the thesis deals with the nuclear magnetic resonance and NMR experiments, which had been used for the structure detecting of unknown substances (1 H NMR, 13 C NMR, gHSQC, gHMBC, gCOSY a NOESY). In the last part the thesis summarizes the results of the experiments.
|
|
|
Gemellologic methods (twins studies) in studying genetic factors of diseases
Mizerová, Veronika ; Kovařík, Miroslav (advisor) ; Fikrová, Petra (referee)
Veronika Mizerová Gemellologic methods (twins studies) in studying genetic factors of diseases Bachelor thesis Charles University in Prague, Faculty of Pharmacy in Hradec Králové Medical laboratory technicien Abstract: This work in its first part generally sums up the genetics of monozygotic and dizygotic twins, describes the differences and similarities during the transfer of the genetic information. In further parts it deals with the methods of geminology and their application to the genetic factors of diseases. In the last part it concerns with the heredity of complex characteristics and epigenetics in twins. Keywords: twin studies, monozygotic twins, dizygotic twins, genetic factors
|
guest ::
