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The sign language current education at elementary schools for hearing impared
Karolová, Soňa ; Červinková Houšková, Kateřina (advisor) ; Hudáková, Andrea (referee)
This bachelor thesis deals with the current situation of Czech sign language (CSL) acquisition at elementary schools for hearing impaired children. At first, the process of teaching CSL is explained, including sign language in the context of teaching curricula, existing didactic materials, testing children's knowledge in CSL, assessment in CSL and required personality traits and education of CSL teachers. This part is followed by description and explanation of ongoing problems and frequent questions connected with teaching CSL at schools for hearing impaired children. The results that can be found in my work are based on relevant specialized literature and visits two schools for hearing impaired in Vala ské Mezi í í and Praha Radlice where I had an oportunity to observe Czech sign language classes. Consequently, I discussed the situation with the Czech sign language teachers. A concrete result of this work is a conclusion that the most serious problem of CSL education is the lack of CSL didactic materials and vague position of the subject in school curriculum.I believe that my thesis will contribute to better mapping of the whole situation of Czech sign language teaching and its acquisition. Moreover, the work can serve as a source of information for Czech sign language teachers as well as...
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Deaf interpreters working in a team
Pešková, Kateřina ; Macurová, Alena (referee) ; Červinková Houšková, Kateřina (advisor)
Bakalářská práce "Neslyšící tlumočníci v pracovním týmu" by měla sloužit jako základní vhled do problematiky týmového tlumočení, kdy jsou členy týmů neslyšící tlumočníci. První, teoretická část, se věnuje druhům týmové spolupráce, základním pravidlům pro sestavování tlumočnických týmů a práci v nich. Dále se zabývá neslyšícími tlumočníky - jaká kritéria by měli splňovat pro výkon této profese a jakým způsobem je pro ně závazný Etický kodex tlumočníka. V neposlední řadě se zde vymezují pravidla pro spolupráci v týmu s neslyšícím tlumočníkem. Praktická část práce obsahuje výčet situací, v nichž je vhodné přizvání neslyšícího tlumočníka a ukazuje přínos neslyšícího tlumočníka pro konkrétní situace. Každý typ tlumočené situace je demonstrován na modelové situaci, která obsahuje schéma rozmístění tlumočníků a popis jejich práce při tlumočení i v přípravné fázi. Závěr práce je věnován stručnému vhledu do situace neslyšících tlumočníků u nás.
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Determination of coagulation factor VIII in haemophilia A patients;Evaluation of different methods of measurement depending on the type of mutations in the gene for factor VIII.
HOUSKOVÁ, Kateřina
Hemostasis is essential to life; it is the ability of organism to stop bleeding and to maintain the fluidity of the blood in an intact vascular bed at one time. Factor VIII is called antihemophilic globulin or antihemophilic factor. It is a plasma glycoprotein composed of two noncovalently associated chains. One chain is a heavy one, comprising domains A1- A2- B and the light chain composed of the domains A3- C1-C2. FVIII activity was measured in two ways from historical reasons a) a one-phase method, where a mixture of FVIII deficient plasma and patient plasma is analyzed using APTT assay; the absence of FVIII in the patient plasma leads to lengthening of the time, b) two-phase method, where the first step leads to formation of FVIIIa and FXa and in the second phase there are thrombin and fibrin created. Two-phase method is difficult to implement in routine laboratory, and therefore it was stopped using during time. This method was substituted by the chromogenic method after development of the chromogenic substrates, where there is in the first step created FVIIIa and FXa in the presence of FIXa, phospholipids and Ca2+, and in the second step there is formed a yellow coloration by the addition of the chromogenic substrate. FVIII deficiency causes a severe bleeding disorder, hemophilia A. I performed measurements from May to September 2013 at Coagulation laboratory at the Institute of Hematology and Blood Transfusion in Prague, where I was employed. I examined in total 76 patients, hemophiliacs A, who were at least 8 days without any treatment or substitution. I assigned numbers to patient's samples to ensure anonymity of patients. I worked with the automatic coagulation analyzer STA- R Evolution? from Diagnostica Stago, which works on the principle of photometry and chronometry. I determined the factor VIII by one-phase method and two-phase method and I compared the results. The genetic part of the work was analyzed in the genetic laboratory, which is part of our department. I worked up the results obtained from both methods in 76 patients to the table and the graph. The group included 14 (18 %) moderate and 56 (74 %) of mild hemophiliacs, then 6 (8%) hemophiliacs who did not meet the criterion of a mild hemophilia A, but clinically they belonged into mild hemophiliacs. Based on the stated criteria, we found out that 15 (20 %) patients had a ratio of FVIII: C1st/FVIII: Chr or FVIII: Chr / FVIII: C1st 0.6, they differed significantly in their values set by one-stage clotting FVIII and FVIII set by the chromogenic method. A total of 11 patients with FVIII activity were higher in the single-phase method. At three patients FVIII: C1st was even on the upper limit of the normal value, while FVIII chromogenic method gave on average 16%. We managed to find a causal mutation in the FVIII in 14 patients with "the different results", we could not investigate 1 patient genetically because of the missing genetic material. Mutations in patients with lower activity of FVIII set up by the chromogenic two-phase method were concentrated predominantly into the A3 domain; mutations in patients with FVIII a lower activity set up by one-phase clotting assay were concentrated in the A2 domain. The results presented show, that diagnostic of any patient with mild or moderate hemophilia A should include determination of FVIII by both methods; FVIII: C1st and FVIII: Chr.
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