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Possibilities of clinical use single and tandem shock waves.
Zeman, Jan ; Beneš, Jiří (advisor) ; Kneppo, Peter (referee) ; Bolek, Lukáš (referee)
Shock waves have been used in medicine for more than 30 year. At the beginning was mainly use for lithotripsy, but today is also applied in other fields of medicine, such as orthopedics, rheumatology and others. Single shock wave is one shock that usually is repeated every 1-1.5 seconds. By contrast tandem shock waves are two shocks consecutively (ideal interval between shocks is from 8 to 15 microseconds), that are repeated. In this work we investigated the clinical use of single and tandem shock waves that are generated entirely new source. It is based on the principle of multichannel discharge. It was found that a single shock wave can destroy the union between bone and bone cement, this effect could be used in orthopedics. Single and tandem shock wave can damage the tumor in vivo, but the principle damage is different. Tandem shockwave is able to cause damage in a depth of acoustically homogeneous medium and enhances the effect of chemotherapy. It would therefore be possible to used single and tandem shock waves in oncology either alone, or their combination with other chemicals. Functional sample of clinically usable applicator of shock waves with a new source was made for these applications. Powered by TCPDF (www.tcpdf.org)
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Possibilities of clinical use single and tandem shock waves.
Zeman, Jan ; Beneš, Jiří (advisor) ; Kneppo, Peter (referee) ; Bolek, Lukáš (referee)
Shock waves have been used in medicine for more than 30 year. At the beginning was mainly use for lithotripsy, but today is also applied in other fields of medicine, such as orthopedics, rheumatology and others. Single shock wave is one shock that usually is repeated every 1-1.5 seconds. By contrast tandem shock waves are two shocks consecutively (ideal interval between shocks is from 8 to 15 microseconds), that are repeated. In this work we investigated the clinical use of single and tandem shock waves that are generated entirely new source. It is based on the principle of multichannel discharge. It was found that a single shock wave can destroy the union between bone and bone cement, this effect could be used in orthopedics. Single and tandem shock wave can damage the tumor in vivo, but the principle damage is different. Tandem shockwave is able to cause damage in a depth of acoustically homogeneous medium and enhances the effect of chemotherapy. It would therefore be possible to used single and tandem shock waves in oncology either alone, or their combination with other chemicals. Functional sample of clinically usable applicator of shock waves with a new source was made for these applications. Powered by TCPDF (www.tcpdf.org)
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Electronic support for learning. Use of the multiple steps e-learning concept in medical biophysics
Nosek, Tomáš ; Hanuš, Josef (advisor) ; Bolek, Lukáš (referee) ; Kolářová, Hana (referee)
Electronic support for learning -Use of the multiple steps e-learning concept in medical biophysics The aim of our work was to create and test a new concept of education based on modern e-learning methods. It should respond to our needs of higher individualization of education in terms of time, content and place. We named it the MSL concept - the Multiple Steps Learning concept. In the spirit of our concept we created three courses in LMS Moodle as support of practical education in Medical Biophysics. We started a pilot project to test the quality of the courses and their impact on knowledge of students. For evaluation of the courses we used our own modification of eLSE methodology. To test the impact on knowledge we compared the results of end-term tests between subsequent years - the education with and without e-learning support. The results of our pilot project show clearly that we created good quality courses. However, the impact of the new method on knowledge is not clear. According to the collected data the difference between both methods of education is not statistically significant but we experienced some serious problems during data acquisition and that is why the validity of the data is at least disputable. These problems gave rise to a new methodology of gained knowledge comparison which was an...
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