Národní úložiště šedé literatury Nalezeno 14 záznamů.  1 - 10další  přejít na záznam: Hledání trvalo 0.01 vteřin. 
A Preliminary Study of Modification of 7-Deazaadenine with a Complex of Osmium Tetroxide with 2,2 '-Bipyridine
Vítová, Lada ; Havran, Luděk ; Fojta, Miroslav ; Šedo, O. ; Zdráhal, Z. ; Vespalec, Radim
Reactivity of a purine nucleic base analogue 7-deazaadenine (A*) in short oligodeoxynucleotide (ODN) towards an osmium tetroxide complex with 2,2'-bipyridine (Os, bipy) was investigated by means of electrochemistry, capillary electrophoresis and MALDI-TOF mass spectrometry. Electrochemical measurement, electrophoretic analyses and mass spectrometric analyses of reaction mixture proved that ODN with an A* residue yields an osmium adduct with properties similar to those exhibited by the well-known adduct of thymine.
Study on the Electrophoretic Behaviour of Short Oligodeoxyribonucleotides in Fused Silica Capillaries. A Preliminary Communication
Vítová, Lada ; Fojta, Miroslav ; Vespalec, Radim
Effects of background electrolyte pH, composition and concentration on the electrophoretic transport of short oligodeoxyribonucleotides (ODNs) in fused silica capillaries have been investigated in the presented study. Mobilities and separation efficiencies of ODNs peaks varied with all three background electrolyte characteristics. Just changes in the background electrolyte characteristics and acid-base properties of ODNs are not sufficient for a systematic explanation of the observed variations. Despite the indicated complexity of ODNs electrophoretic behaviour, we show that very high separation efficiencies of ODNs peaks can be achieved in background electrolytes of physiological pH.
Electrochemical Investigation of Different Boron Cluster Compounds in Water-based Electrolytes
Fojt, Lukáš ; Vespalec, Radim ; Fojta, Miroslav ; Grüner, Bohumír
Boron cluster compounds (BCC) belongs to one or the proud sing compounds which ace used for medical treatment Their use for biochemical purposes is connected with use of water-based environments. Up to now, the BCC were predominantly characterized in non-aqueous milieus Therefore, we decided to undertake electrochemical research of BCC in water-based electrolytes. We have investigated several boron clusters with structures containing different number of vertexes (from 3 to 18), The structures were modified by endo- and exo- skeletal substituents. All used BCC were electrochemically active in broad potential region. which implies their possible use as biomarkers with tunable electrochemical response.
Kapilární elektroforéza v analýze chirálních látek
Vespalec, Radim
Je podán přehled metodologie chirálních separací kapilární elektroforézou ve volném roztoku.
Mobilita v kapilární elektroforéze
Vespalec, Radim
Jsou definovány a diskutovány základní pojmy v kapilární elektroforéze.
Kapalinová chromatografie a kapilární elektroforéza - partneři nebo soupeři?
Vespalec, Radim
Byly diskutovány přednosti, omezení a komplementarita obou instrumentálních separačních technik.
pK determination of sparingly soluble weak bases
Vlčková, Markéta ; Barták, P. ; Vespalec, Radim
pK values of sanguinarine and chelerythrine have been determinedat conditions of planned interaction measurements and renasons for the pread of published pK data of these weak bases have been investigated.
Chiral separation of charged cluster boranes
Slavíček, V. ; Vespalec, Radim
Capillary zone electrophoresis is effective instrumental technique for chiral separations of charged cluster boranes if β-cyclodextrin serves as chiral selector.
Studium elektroforetických vlastností sanguinarinu a chelerythrinu
Vlčková, Markéta ; Vespalec, Radim
Technikou kapilární zónové elektroforézy byly stanoveny pK hodnoty alkaloidů sanguinarinu a chelerythrinu. Pro potřeby fotometrické detekce byly dále změřeny UV-absorpční spektra obou forem těchto alkaloidů.
Chiral separations of charged boranes and carboranes by CZE
Slavíček, Viktor ; Vespalec, Radim
The applicability of capillary zone electrophoresis for achiral and chiral analysis of deltahedral boranes was proved. Twelve derivatives of different structural types were chirally separated with ß-cyclodextrin as a chiral selector.

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