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Specifics of work of nurses in the centers of biological treatment.
MENCLOVÁ, Šárka
Specifics of the Work of a Nurse in Biological Therapy Centres? The bachelor thesis was written in theoretical form with the aim to map the problems of biological therapy. The method of research and analysis of the available present sources related to the topic was applied to the thesis elaboration. Biological therapy represents a new type of treatment trying to create such a compound that is capable of targeted immune system suppressing or strengthening to influence a pathological process in an ill or impaired organism as accurate as possible. Because of high costs the treatment by biological preparations had to be concentrated to centres. Quality teams of people that are able to assess effectively for which patient the therapy is suitable and safe work at the centres. Patient registers enable efficient treatment and long-term monitoring of medical safety. Attention is also paid to equipment and environment of the centres. The chapter Specifics of Nurse Work focuses on professional knowledge and skills of a nurse in biological therapy application. The main task of a nurse is to provide complex, individual holistic nursing care based on quality verbal and non-verbal communication and educational activity. The next part deals with the individual spheres of medicine with the best experience with biological therapy. In gastroenterology, where idiopathic intestine inflammations of Crohn?s disease and ulcerous colitis are treated by means of TNF-? blocking substances, the substances are administered in the form of infusion or subcutaneously. Nurses thus have to be aware of treatment process, treatment principle and side effects linked to the therapy. Excellent results are achieved with biological therapy in the rheumatology centre in treatment of rheumatoid arthritis, ankylosing spondylitis also known as Bechterew's disease, psoriatic arthritis and juvenile idiopathic arthritis. ATTRA Registry, which is one of the most important tools for patient monitoring from the beginning of the therapy, is also mentioned here. The work of nurses in the oncology centre focuses on monitoring the side effects linked to the therapy. Side effects linked to biological therapy are more specific than those in cytostatic therapy. It thus depends on nurse?s observation skills, her ability to decide what symptoms should be focused on during the therapy and ability to respond to them in timely manners. The last centre analysed in the thesis is the dermatology centre, where they have experience with therapy of a chronic disease called psoriasis vulgaris. The information provided from the available data has shown us that although the therapy is highly costly, its purposeful application is economically effective at least thanks to the fact that timely commencement of therapy enables patient life quality improvement without possible disability. Although the therapy is not able to cure the patients completely, its main goal is to slow down the disease prognosis and to free the patients from the pains linked to the disease.
Complex Treatment of Patients with Bechterew´s Syndrome
ARCIMOVIČOVÁ, Petra
The bachelor thesis titled "Complex Treatment of Patients with Bechterew´s Syndrome" suggests therapeutic possibilities of the disease. Bechterew´s syndrome is a frequent topic of scientific papers but the complexity of treatment is not always considered. A major part of the theoretical section presents the disease with its signs and symptoms, and also discusses the much debated causes, the progression and phases of the disease. The thesis focuses on the psychosomatic approach; it discusses potential influences and other factors, specifically genetic and antigen factors, a potential connection with bacterial diseases, the function of intestinal microflora and its relation to dietary habits. Another important topic is influence of specific personality traits, as well as the implication of the patient´s social interactions in the early childhood on the behaviour in an adult age. The research results in five examinations of patients with Bechterew´s syndrome including personal history, kinesiology examination and a two-hour interview with each patient. The data are qualitatively analyzed. There are two research questions: the first explores which physical, psychological, social and spiritual factors may improve the disease; the second looks into factors which may aggravate it. On the one hand, in the majority of cases the most important factors seem to be the diet, physical activity, specific personality traits and faith in God. On the other hand, the diversity of patients - interviews with patients taking place in a spa, a rehabilitation centre, at home - leads to very different personal opinions and feelings. The last interview, number 6, offers a homeopathic point of view. In spite of the fact that the research sample is relatively small, the research data are very useful, even though no definite conclusions can be made. The thesis may contribute to the knowledge of health workers specializing in the treatment of Bechterew´s syndrome and to the training of physical therapists.

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