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Kinesiotherapy of patients with Parkinson's disease
Kadeřábková, Michaela ; Savková, Pavlína (advisor) ; Molnár, Petr (referee)
Author: Michaela Kadeřábková Department: Department of rehabilitation medicine Title of the master thesis: Kinesiotherapy of patients with Parkinson's disease Supervisor: Mgr. Pavlína Savková Number of pages: 81 Number of attachments: 6 The year of presentation: 2012 Key words: Parkinson's disease, rehabilitation, tremor, rigidity Bachelor thesis deals with in the theoretical part about the origin, clinical symptoms and especially the treatment of PD. The treatments focuses primarily on rehabilitation treatment and analyzes kinesitherapy and its possibilities. The practical part is devoted to treatment of patients who suffer from this disease. Kinesiotherapy in selected patients is concentrated on major problems and their physical shortcomings.
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Correlation analysis of Parkinson's disease in the acoustic field
Vošček, Jakub ; Mekyska, Jiří (referee) ; Smékal, Zdeněk (advisor)
The topic of this bachelor thesis is the correlation analysis of Parkinson’s disease in the acoustic field. The first part is about the Parkinson disease and its symptoms. It looks closer on problems with speech production, which is called hypokinetic disarthria, and describes the causes of the problems as well as the kind of treatment that is used. The next part involves a study of the pre–processing of signal, i.e. removing the direct component, a preemphasis and a segmentation to smaller frames. Afterwards, individual parameters are calculated in the next step. It is also necessary to calculate simple statistics, for example a median, a standard deviation, etc. after the calculation of some parameters. The calculation of Pearson’s and Spearman’s correlation coefficients is included. Moreover, a block diagram for the data processing is suggested, which involves a description of the functions of the individual blocks. The program is explained in the practical part, which also features parts of the tables with parameters' values and the calculated coefficients. As the conclusion of the work, there are graphs which display correlations of the parameters and the paraclinical data.
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Nursing care for a client suffering from Parkinson's disease
SVOBODOVÁ, Pavlína
Current state of the research field: Parkinson's disease is a neurodegenerative disease affecting basal ganglion. Brains of patients suffering from Parkinson's disease are damaged by death of dopamin producing cells in substantia nigra. Cause of this cell death is still unknown. Symptoms of Parkinson's disease include tremor, rigidity, aknesia and bradykinesia, disturbances to posture and gait, hypophonia, dysarthria, micrographia, eye movement abnormalities and decreased blink rate, hypomimia and mental, vegetative, sensoric and sensitive dysfunctions. In diagnosis of Parkinson's disease a medical history collected by a physician in collaboration with a nurse is used. Nurse assists a client with filling a questionnaire regarding nonmotoric symptoms. Furthermore, she carries out a L-dopa test. If symptoms are mitigated after drug administration, the test is considered being positive. Other examinations requiring nurse's assistance are DaTscan and histology. Pharmacological treatment relies on substitution of missing dopamin and hence restoring dopaminergic transfer. Nurse administers Levodopa, dopamin agonists or COMT inhibitors according to physician's decision. In neurosurgical treatment, where deep brain stimulation is used, nurse conducts preoperative and postoperative care. Pharmacological and neurosurgical treatment could be also combined with supportive treatment, about which should a nurse inform a client. Major nursing care complications in Parkinson's disease which are monitored by a nurse includes limited mobility, walking problems, tremor, impaired self-management, stress overload, anxiety, speech disturbances and voice disorders, constipation, urinary incontinence, impaired balance and frequent falls, inappetance and swallowing difficulties. Aims: To map problems in nursing care for a client suffering form Parkinson's disease from client's and nurse's points of view. To map nursing interventions in Parkinson's disease therapy from client's and nurse's points of view. Methods: Qualitative research in form of an in-depth interviews with nurses and clients was carried out. All interviews were recorded as a verbatim copy and coded using pencil and paper open coding method. Created codes were grouped into categories and subcategories. Interviews were carried out in March 2014. Participants: First set of participants comprised of ten nurses caring for Parkinson's disease suffering clients, four of them working at a department of neurology, four at a department of long-term care and aftercare, and two nurses providing a home care. Other set of participants comprised of six clients suffering from Parkinson's disease, five of them were members of Parkinson club České Budějovice, and the last was living in a village near Náměšť nad Oslavou. Results: Using the open coding method three categories, focused on particular topic, each containing several subcategories, were picked from interviews with both participant groups. Categories Nursing care problems, Nursing care and Specific interventions are identified in the first part. In the category nursing care problems nurses mostly agreed on a self-management deficit, movement difficulties, increased fall risk and communication problems. Aktivisation, motivation, rehabilitation, self-management training, regular drug administration and family participation were most frequently mentioned in the category nursing care. In the category specific interventions nurses focused on interventions directly related to particular problems. In the second part of the research categories Every day tasks management, Nursing care and Specific interventions are identified. In the every day tasks management category clients mentioned necessity of other parsons assistance in self-management, and movement difficulty and stiffness are considered being most annoying.
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Nutrition and cerebral neurodegenerative diseases
Šálková, Michaela ; Vespalcová, Milena (referee) ; Vránová, Dana (advisor)
This bachelor‘s thesis is literary research and its topic is focused on the effect of nutrition on the development of neurodegenerative diseases. The thesis is divided into four parts. The first part deals with the structure and physiology of the human brain. In the second part are described all essential nutrients which the brain needs to maintain its functions. The third part focuses on neurodegenerative diseases and their epidemiology and pathophysiology. In this part are also examined nutrients which could be possibly useful in the prevention or which could be involved in the pathophysiology of the disease. Explored diseases include dementia, Alzheimer’s disease, Parkinson’s disease and unipolar depression.The aim of this thesis was to find accessible literature focused on this topic and make a discussion.
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Degree of Parkinson's disease estimation based on acoustic analysis of speech
Ustohalová, Iveta ; Kiska, Tomáš (referee) ; Galáž, Zoltán (advisor)
The diploma thesis deals with the non-invasive analysis of progression of Parkinson´s disease using the acoustic analysis of speach. Hypokinetic dysarthria in connection with Parkinson´s disease as well as speech parameters are described in this work. Speech parameters are sorted according to the speech component they affect. The work uses the phonation of vowels "a" speech task as the most commonly used speech task in the field of pathological speech processing, because of its resistance to demographic and linguistic characteristics of the speakers. Based on obtained knowledge, in MATLAB development enviroment were created systém for UPDRS III scale estimation. The UPDRS III scale is based on subjective diagnosis given by the doctor. At first, one individual parameter is used for the UPDRS III scale value estimation. Then the feature selection using SFFS algorithm is applied to gain feature combination with minimal estimation errror. Attention i salso paid to correlation between individual symptoms and UPDSR III scale.
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Tool for analysis of subject's movements in functional magnetic resonance measurements.
Šejnoha, Radim ; Lamoš, Martin (referee) ; Gajdoš, Martin (advisor)
This diploma thesis deals with an analysis of subject’s movement during measurements with funcional magnetic resonance imaging (fMRI). It focuses on methods of a movement artifacts detection and their removal in fMRI images. Thesis deals with metrics which are used for the movement rate of measured subjects evaluation. Metrics and a correction of movement are implemented into the programme in MATLAB. Comparison of subjects suffering from Parkinson’s disease with a group of healthy control was carried out. Tresholds of individual metrics were suggested and a criterion for the removal of subjects with high movement rate was determined.
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Analysis of Parkinson's disease using segmental speech parameters
Mračko, Peter ; Mekyska, Jiří (referee) ; Smékal, Zdeněk (advisor)
This project describes design of the system for diagnosis Parkinson’s disease based on speech. Parkinson’s disease is a neurodegenerative disorder of the central nervous system. One of the symptoms of this disease is disability of motor aspects of speech, called hypokinetic dysarthria. Design of the system in this work is based on the best known segmental features such as coefficients LPC, PLP, MFCC, LPCC but also less known such as CMS, ACW and MSC. From speech records of patients affected by Parkinson’s disease and also healthy controls are calculated these coefficients, further is performed a selection process and subsequent classification. The best result, which was obtained in this project reached classification accuracy 77,19%, sensitivity 74,69% and specificity 78,95%.
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State of the art speech features used during the Parkinson disease diagnosis
Bílý, Ondřej ; Smékal, Zdeněk (referee) ; Mekyska, Jiří (advisor)
This work deals with the diagnosis of Parkinson's disease by analyzing the speech signal. At the beginning of this work there is described speech signal production. The following is a description of the speech signal analysis, its preparation and subsequent feature extraction. Next there is described Parkinson's disease and change of the speech signal by this disability. The following describes the symptoms, which are used for the diagnosis of Parkinson's disease (FCR, VSA, VOT, etc.). Another part of the work deals with the selection and reduction symptoms using the learning algorithms (SVM, ANN, k-NN) and their subsequent evaluation. In the last part of the thesis is described a program to count symptoms. Further is described selection and the end evaluated all the result.
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Care for People with Parkinson´s Disease in South Bohemia Region
KROUPOVÁ, Denisa
Theoretical part of this bachelor thesis dedicates to a Parkinson´s disease problematic. There is described an origin of this disease. A next topic is a progress and a prediction of the disease. This disease is a progressive one. It means that over time the situation is getting worse. The Parkinson´s disease prediction has completely changed since 80s, when levodopa has become a basic medicine. A Parkinson´s disease treatment helps to getting slow of the disease progress. That guarantees to a diseased people to live almost a full life. Pharmacological treatment consists of a substitution medical treatment, compensatory and adjuvant one. Non ? pharmacological treatment is guaranteed by different therapies and pedias from which the main place has physiotherapy. Surgical treatment is dedicated only for people, where pharmacological treatment has not got enough effects. The last chapter deals with health and social services for people with Parkinson´s disease. Health services are provided by both, public and private medical facilities. I divided into two parts the social area. The first one are the services which can be used by people with this disease and the second one are the benefits for people with disabilities. These people are undoubtedly disabled by Parkinson´s disease too. The main aim of the bachelor thesis is to find out, which effects of Parkinson´s disease have on the life of people with this disease. An intermediate aim is to find out, which health and social problems people with Parkinson´s disease could have in the South Bohemia region. Due to the aims of the thesis, I chose a quality research. I used the methodology of asking, a semi ? structured interview. This interview was consisted from seven questions, which were concerned private, family, working, social, economical areas and problems with which people with this disease could meet in the area of health and social care in the South Bohemia region. High quality data are analysed by a methodology of capture patterns (gestalts). A research group consists from six respondents who were chosen by deliberate choice. The results of the thesis show that Parkinson´s disease is more or less in touch with all parts of life of people with this disease. The symptoms influence the private life too, where make daily, common functioning, more difficult. In the family area, the impacts of Parkinson´s disease are projected in the relationships. Two of six respondents said, that the relationship was stronger, but one respondent said, that is was a breaking up of his relationship. The working area is bothered too. Loss of endurance, inability of performance in a manual working and limited possibilities, all of these are the reasons which blocked the manual working. On the other hand, three of the respondents, didn´t have to leave their jobs due to the Parkinson´s disease. Only one respondent stated that expenditure increased due to Parkinson's disease. None of them feels to be dependent on the family members. The medicaments are for free for the people with this disease, and they couldn´t pay for them. Among the results which affect people with this disease in the health care service we can say there isn´t health centre in the South Bohemia region. One respondent wasn´t satisfied with the neurology care. In my opinion is low knowledge in this part of a social care. Two of six respondents, didn´t know where to get information. From social contributions there exists just contribution to mobility. Four respondents have a card for disabled people. The results of this thesis showed that this disease brings many different limitations. This work could be the biggest benefit for people with this disease as well for their family members, friends and others who are interested in this problem. The work could bring the inspiration for activity of Parkinson Club České Budějovice.
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Health and social problems of Parkinson´s disease
PAŤHOVÁ, Eva
The Parkinson´s disease is a chronic disease whose syptomps affect human life to a consederable extent. If follows the results of the research that seniors have a knowledge in the basic fields, i.e. they know what physical system is affected by the Parkinson´s disease has a slow, sneak course. they are also aware of the most frequent method of therapy (pharmacological) and know that the Parkinson´s disease often stimulates tendčency to depresssions. However, few of the questioned seniors were aware of the national and local existence of the Parkinson assotiation and the age group in which the Parkinson´s disease occurs most frequently.
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