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Continuous measurement of blood pressure
Kopčil, Petr ; Chmelař, Milan (referee) ; Nováková, Zuzana (advisor)
This paper deals with the physiology of cardiovascular system, explains elementary principles related to blood flow physiology and describes some basic mechanisms for regulation and blood pressure measurement. The paper also includes a description of the medical device, known as the Finometer (FMS, Netherlands), for continuous non-invasive blood pressure measurement and suggests a way to data export from this device to a text file. It introduces user friendly application to manage recorded data written in MATLAB. There is a statistical test to assess the difference between two statistical data files in the last chapter of this paper which includes a comparison our results with studies made in Czech Republic and other countries too.
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Influence of the surrounding tissue on the stresses in brain arterial aneurysms
Lipenský, Zdeněk ; Burša, Jiří (referee) ; Polzer, Stanislav (advisor)
This thesis is focused on stress in brain aneurysms. It consists of three parts. First part is aimed for gaining information about the topic from scientific resources. Next part consists of analyses of geometry of cerebral aneurysms on the computed wall stress. Analyses are performed on four basic geometrical models and results are being discussed. The risky areas in each investigated shape have been identified as well as the comparisons of stress between those shapes have been performed and the most dangerous shape among investigated shapes has been determined. Third part investigates the influence of surrounding tissue on the brain aneurysm. Conclusion of this thesis is that brain gray tissue has positive yet negligible effect on the computed wall stress.
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Measurement of cardiovascular parameters
Kratochvíla, Jiří ; Čmiel, Vratislav (referee) ; Kolářová, Jana (advisor)
The aim of the bachelor’s thesis is to get acquainted with the measurement of cardiovascular parameters, to realize the measurment of these parameters, to analyze them, show the statistic procedure of verifying hypotheses in this spere and finally the presentation of measured data including automatical detection of the heart rate from ECG signal in created program in Guide of Matlab system. On the basis of the theory was done the measurment on own suggestion with the Biopac system and with the quicksilver tonomether. The parameters, that were measured on the group of five people: ECG, blood pressure and the pulse frequency before and after the load. After the data processing was done the statistic analysis, the aim of this analysis was to show the procedure of verifying hypothesis, if and how are these measured parameters of cardiovascular system changing. After that the measured data were transported into Matlab system. The presentation of measured data (created program) contains the time domain and spectral analyses (using Fourier transform) of ECG signal, automatical detection of the heart rate from ECG signal, analysis of the heart rate variability (HRV) – tachogram together with detailed analysis of HRV spectra (spectra of heart rate variability – relating with parasympathetic and sympathetic activity), that are using in clinical practice too, just as the other measured parametres of the cardiovascular system.
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Literature search of possibilities of computational modelling of brain aneurysms
Lipenský, Zdeněk ; Polzer, Stanislav (referee) ; Burša, Jiří (advisor)
This bachelor thesis is focused on gathering general information about a cerebrovascular disorder called Cerebral Aneurysm (or also Brain Aneurysm) which is a medical condition consisting in an abnormal bulging outward of one of the arteries in the brain. The initial attention is given to the human cardiovascular system, a description of which is fatal for understanding the problem of brain aneurysm. The next attention is focused on the solution of eliminating the tension within the aneurysm by using knowledge gained in lectures "Flexibility and Strength II" during the sixth semester. The last chapter shows a summary of three works dealing with computational modeling of cerebral aneurysm.
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Doppler measurement of vessel parameters
NÁTHEROVÁ, Markéta
Ultrasound investigation is the most common and most readily available current advanced diagnostic method. Ultrasound can be used to track and image moving structures such as cardiac valves or flowing blood {--} these methods are based on the so-called Doppler phenomenon. Using the Doppler phenomenon, it is possible to determine the velocity and direction of movement of the measured object. The objective of this work was to track the changes of vascular flow and pulse rate depending on the degree of tolerance of exercise attained by the test persons, the stress (load) and ambient temperature changes. For this purpose, 2 groups were defined where the first group consisted of individuals adapted to the stress, while the members of the second group were untrained. To measure the vascular parameters we used a Doppler meter, HiDop 300. The LCD display of the instrument, or alternatively the monitor of a connected computer, provide images of the measured spectral Doppler curve as well as its parameters (heart rate HR, resistance index RI, pulsatility index PI, systolic/diastolic ratio, mean frequency). The work is concerned with the impact of physical load and cold-related stress on the circulatory system in the vessels. The haemodynamics of the vascular system depends on the type and intensity of the load. The formulation of results of the work, however, must account for a number of internal factors (age, sex, health {\dots}) and external factors (ambient temperature, air flow {\dots}) that are themselves associated with various changes in the circulatory system. For example, reduction of peripheral vascular contractility in the elderly, disruption of vascular wall elasticity by depositing fatty substances or increased heart rate due to the stress stimulus. The main advantage of a Doppler instrument and all ultrasound methods is to be seen in the fact that it is a non-invasive method, and has no adverse effects on the investigated person, such as the effects associated with roentgen radiation, provided, however, that appropriate intensity of ultrasound radiation has been chosen.
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Fyzikální modelování srdečně cévní soustavy na ÚT AVČR
Pražák, Josef
The physical modeling remains an important tool for theoretical and practical studies of CVS. Nowadays, the most important applications of physical modeling of CVS are the testing and developing of artificial substitutions of CVS elements and the application of it as a counterpart for mathematical models. On the IT, the physical modeling of the CVS flow phenomena is developed since the last century (more then six years) in the Laboratory of biomechanics. In its contemporary state, the IT physical model of CVS represents a universal system (construction kit) suitable for a large class of applications.
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