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Determination of aminoglutethimide using HPLC-ED on carbon pastes
Vlachová, Karolína ; Šestáková, Ivana (referee) ; Zima, Jiří (advisor)
In this thesis, the determination of AGT, sooner used as anticancer drug, especially for the treatment of breast cancer in postmenopausal women or for the treatment of prostate cancer, by high performance liquid chromatogramy with UV spectrophotometric detection (HPLC-UV) and electrochemical detection (HPLC-ED) on carbon paste electrodes (CPEs) was studied. CPEs were prepared from glassy carbon microspheres and different pasting liquids - routinely used mineral oil (CPE-MO) and less commonly used tricresylphosphate (CPE-TCP) and silicone oil (CPE-SO). The concentration dependences of AGT were measured by HPLC-UV with detection wavelength 242 nm, by HPLC-ED with a working potencial of +1,3 V for CPE-MO and + 1,1 V for CPE-TCP in mobile phase containing phosphate buffer (pH 4) and methanol 50:50 (v/v). The following limits of detection were achieved - 3,6. 10-7 mol.l-1 for UV spectrophotometric detection, 2,5. 10-7 mol.l-1 for electrochemical detection with CPE-MO and 9,7. 10-7 mol.l-1 for electrochemical detection with CPE-TCP. AGT was also determined in model samples of urine. With HPLC-UV it was not possible to detect AGT, because of the interferences of other compounds. With HPLC-ED on CPE-MO the limit of detection 5,2. 10-7 mol.l-1 AGT was achieved. KEY WORDS Aminoglutethimide HPLC with UV...
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Surgical sex conversion
Dohnalová, Lenka ; Šamánková, Marie (advisor) ; Kříž, Jan (referee)
The aim of this thesis is to concentrate to inform the comunity with less known problems of nursing the patients with disorders of sexual identification - with transexuality. The persons with this disorder have genetic and somatic equipment belong to one sex, however their sexual identification is orientated to contrary gender. Surgical conversion of sex of transexuals forms oni y one of the aspects by complex approach to this complicated disorder. The decision when the surgery is indicated is up to sexologist and authorized by the committee. The commision decision is based on detailed and prolonged psychological approach to everyone. The observation is pointed at adaptation for new social status a:fter longtime hormonal treatment and follows a:fter operation and o:fficial conversion ofthe gender as well. Powered by TCPDF (www.tcpdf.org)
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Prevention of breast cancer
Rybková, Helena ; Šafář, Petr (advisor)
Breast cancer is one of the most important tumor diseases of our female population. In his presence keeps sad victory. It also assessed a five-year mortality survival in comparison with other comparable countries unsatisfactory. The thesis is mainly concentrating on the prevention breast cancer, both primary and secondary risk factors breast cancer and mammography screening. In the fight against breast cancer is early detection is still a priority and increasing the effectiveness of treatment.
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Long-term financial assets and income arising from it
Pejlová, Gabriela ; Skálová, Jana (advisor)
This bachelor thesis is devoted to the characteristics of long-term financial assets and income that result from it. It is focused on the accounting treatment of this issue. It concentrates on equity securities and shares and bonds, since they are the most important part of long-term financial assets. The work is divided into several chapters, where each describes a certain phase of acquisition, through possession and related income and revaluation of the balance sheet date, to the exclusion of securities and shares. The last part of the work is focused on reporting long-term financial assets in the financial statements.
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Concentration of cobalt in wastewater and its removal using a constructed wetland
PIVONKOVÁ, Eliška
The presented bachelor's thesis discusses monitoring of wastewater in a vegetation wastewater treatment plant in the village Slavošovice, Czech Republic and an efficiency of cobalt removal from wastewater. Cobalt concentration in wastewater was determined using the atomic absorption spectrometry. The analyzed wastewater samples were taken from different parts of the constructed wetland's system in the period from March to September 2015. The obtained results enabled to calculate the efficiency of cobalt removal from wastewater.
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Clients´ Perception of Spa Services in Aurora Spa
KROČÁK, Ladislav
An importance of spa services is especially in the medical treatment, but their economic significance is also very substantial. It significantly affects investment activities and an employment and it contributes to a regional development. Aurora Spa in Třeboň specializes in treating of musculoskeletal disorders, rheumatic diseases, post-traumatic and post-operative conditions and overall recondition of the body. Spa services in Třeboň have been, since a long time ago, associated with a natural healing source, which is abundant in this locality ? a boggy soil. Aurora Spa is not determined only for ill clients, but it is frequently visited by healthy people who undergo reconditioning and relaxation stays. The current trend heads toward to the fact that in the future the spa care covered from the public health insurance, will be in some way limited and clients will have to pay either a part or the entire treatment from their own financial funds. For this reason it is necessary to concentrate with spa service operators on a great clients´ satisfaction with their spa stay, so that they would return to the spa facility. Since I have worked for five years in the area of providing of the treatment services, I followed my bachelor thesis ?Clients´ satisfaction with spa services? by this diploma thesis, in order to re-map the clients´ satisfaction with services provided in above mentioned spa. I wanted to find out whether clients´ attitudes to the provided services had significantly changed from the research in 2009 year in my bachelor thesis. I used for the research the same questionnaire as in the research in 2009 year. 220 respondents were chosen for the research in the period of September 2011; 110 respondents had their stay covered by some of health insurance companies, either in a form of a complex or a contributory spa care and 110 respondents paid their treatment stay from their own funds as private payers. I supposed that men would be more satisfied than women and clients to whom some of the health insurance companies paid the stay, would be more satisfied than clients paying the stay from their own funds. After processing the data, there were not found out any significant differences in the satisfaction between these groups of respondents and in comparison with the research in the bachelor thesis from 2009 year there were not apparent any significant variations in the clients´ satisfaction with the services provided, which confirms, that the spa services in Aurora Spa are still on a very high level. Results of this diploma thesis can be used by employees of Aurora Spa to enhance the quality of provided spa service in all areas and to improve staff access to their clients.
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The mechanisms of specific polutants impact on aquatic communities.
Vaněčková, Hana ; Fuksa, Josef (advisor) ; Hořická, Zuzana (referee)
With a decrease of classic pollution of water ecosystems the importance of PPCP (pharmaceutics and personal care products) increases. Their amount is increasing due to human consumption and thus the input into municipal wastewater and consequently into the surface water, eventually into the ground water increases as well. This bachelor work is a review of scientific literature in the field of PPCP water load. The goal is resuming the results of the studies of the influence of these substances on freshwater aquatic communities. In the beginning the sources of the variability (in time and space) of the concentrations of these substances in rivers are resumed. But the rate of affection of the aquatic communities depends even on the length of exposure, which is longterm with regard to the continuous flow of substances from wastewater treatment plants. That is why the effect of long-term incidence on aquatic communities is intensively studied. The emphasis is put on the incidence of endocrine disruptors (substances disrupting the endocrine system), which affect e.g. the oestral cycle of some kind of exposed populations. There are observed changes in the way of perception of a predator by his prey whereas the escape reactions of the prey happen to be affected. The additive effect of ixtures of...
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Study of Constructed Treatment Wetland Reconstruction for Dražovice Village
Roupec, Ladislav ; Pumprlová Němcová, Miroslava (referee) ; Kriška-Dunajský, Michal (advisor)
The constructed wetlands, which have been being created in the Czech Republic since early 90s, are designed so they do not allow successful removal of ammonia nitrogen. Almost all of these 300 registered constructed wetlands suffer from the colmatage which leads to the lowest effectiveness of treatment in nearly all parameters. The main effort of the Institute of landscape water management is to get rid of bad reputation and to clarify the reason that leads to unsatisfactory conditions of constructed wetlands. The diploma thesis focuses on the selected constructed wetland in Dražovice (850 EO), which removes ammonia nitrogen with the effect just below the limit values in the long term. The pressure of the Morava river basin and Department of environment (Building Authority in Bučovice) has led to the necessity of taking measures leading to the increase of treatment efficiency especially ammonia nitrogen. The diploma thesis includes both, actual project documentation concentrating on the adjustment of watercourse to nitrify ammonia nitrogen, and effective choice of suitable filtration material supported by testing method in situ. The practical part of the thesis deals with the implementation of the technical solution according to the project documentation. The adjustment of the constructed wetland is now nearly before completion. Last adjustments will be taking place during the spring 2017, the final inspection as well as the evaluation of the reconstruction will take place at the end of this year.
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Project to extend water and sewer in the village Brandýsek
Petrová, Michaela ; Synáčková, Marcela (advisor) ; Renata, Renata (referee)
The thesis deals with the project phase of utility services within newly built family homes.
Special attention is paid to the construction of sanitary sewers, water mains and rain water management in urban areas in context of the current legislation. The paper is divided into theoretical and practical part.
The first part focuses on the means and facilities of utility services and on legislation regarding their proposed design and subsequent implementation. The second part concentrates on the construction of particularly selected networks in a specific project. It involves the emerge of new locations within undeveloped areas that closely adjoin the existing community. In this area we find not only a proposed sewerage treatment for wastewater but also water lines for the newly formed 14 building plots. Special attention is paid to the management of rainwater coming from public roads and sidewalks. The construction of the proposed utilities is economically evaluated in the budget costs calculated for building construction.
The conclusion of this paper concentrates on the newly formed building plots that have been pre-engineered for connection to the relevant utilities.
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