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Animal Models of Intrauterine Infections
Schuma, Marek ; Šplíchalová, Alla (advisor) ; Seifertová, Eva (referee)
In mammals, embryonic and fetal development takes place in the mother's uterus under sterile conditions. The embryo, and later the fetus, is connected to the placenta by the umbilical cord and floats in amniotic fluid in the amniotic cavity lined by the amniotic membrane. Preterm birth is associated with decreased weight of newborns and increased morbidity and mortality. Intrauterine infections are one of the leading causes of preterm delivery. Various etiological agents, such as viruses, bacteria, yeasts and protozoa, can cause these infections. These infections induce expression of inflammatory mediators, which participate in triggering of preterm birth. One of these mediators are cytokines. The bachelor thesis is based on a literature review dealing with animal models of prenatal infections, which are exploited in the study of regulatory mechanisms of preterm births or eventually in the study of experimental manipulation of these mechanisms. Various infectious agents and their parts, such as LPS, and the routes of administration are compared. In addition, the advantages and disadvantages of different animal models are discussed with respect to the type of placentation, duration of gestation, animal weight and litter size. The thesis contains the section dealing with experience with a pig model...
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Možnosti ovlivnění násady plodů broskvoní řezem
Hurtajová, Zuzana
This bachelor thesis deals with the styles and the methodology of affecting fruit set for peach by incision. It explores the various ways of cut and its influence to the quality and quantity of fruits. It shows the ways of cut by individual types with the least possible interventions into the lives of the tree, depending on the choice of the variety in different climatic conditions. The quality nor quantity of fruits can not be affected just by incision, that's why this work also deals with fruit thinning since it is an integral part of the cultivation to achieve high quality of peach harvest.
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Dzogchen and its philosophical aspect in Bon tradition
KLOZAR, Karel
The thesis deals with philosophical aspect of Dzhgchen, which is the core of the Yungdrung Bon traditon. It is very special spiritual tradition because of it's very special nondualistic view of man and universe. First part deals with the history and division of it's teachings and it's Dzogchen lineages. Next part focuses on explanation of differences in views of sutra, tantra and Dzogchen, mainly from the standpoint of the view of base, path, fruit, emptiness, clarity, conscioussness and mind and it's nature. Next part provides translation of the text Twelve little tantras and it's deep explanation. Last part, and most important one, focuses on philosophical examination of some key aspects of Dzogchen, mainly on it's view of autenticity of mindnature. This part also compares Pramenides's fragments with some key points of view of Buddhism and Dzogchen, which may lead to some unexpected conclusions about man's thinking and the problem of it's intentionality.
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Women´s in childbed attitude towards cardiotocographical fetal monitoring during childbirth
PAPÍRNÍKOVÁ, Petra
Cardiotocography is a noninvasive method providing information on the condition of the fetus during pregnancy and childbirth. Fetal monitoring has become standard in obstetric care for pregnant women and mothers. The procedures recommended by the Czech Gynecological-Obstetrical Society determine indications of the use of cardiotocography and state rules of how to interpret the results of the method. During physiological childbirth the mother can be observed intermittently, i.e. at regular intervals according to the practice of the specific obstetric department. Pathological delivery, such as breech delivery, delivery of a hypotrofic fetus, fetus with a nonphysiological CTG record, should be monitored continuously. External fetal heart sounds scanning may bring mother some unpleasant restrictions in movement and positioning. When medical staff show preference in observing data obtained by monitoring, it may make the mother fear about the fetus´ condition or raise presumption that midwives do not adequately meet her own needs during the delivery. Nursing care of mothers during cardiotocographical scanning is very specific because a midwife provides care to two subjects - the mother and the child. According to scarce literature on this subject mothers{\crq} in bed attitudes toward cardiotocography vary from the positive view that monitoring protects the fetus and ensures its health to negative feelings of discomfort, limitations, pointless medialization of the natural process, medical personnel distraction and rejection of medical examination. Czech studies, however, have never been conducted and modern literature on this topic does not exist. The research was conducted by the prospective quantitative research using questionnaires. The questionnaires were anonymous and contained 26 questions, 23 of which were closed, 1 was semi-closed and 2 were open. The total number of questionnaires distributed was 101, the target respondents were women in confinement in the Gynecological-Obstetrical clinic of. 1. LF UK a VFN in Praque. The research database was composed of women who were 2 or 3 days after delivery, women with elective Caesarean section were not included into the research. The aim of the research was to learn women{\crq}s in childbed attitude toward cardiotocographical fetal monitoring during childbirth. Three hypotheses were stated: Hypothesis 1 assumes that mothers consider cardiotocographical fetal monitoring to be a source of information on the child condition, and this hypothesis was confirmed. Hypothesis 2 assumes that cardiotocographical fetal monitoring during childbirth restricts the mother{\crq}s movement and relief positioning, and this was confirmed by the research. Hypothesis 3 raises the presumption that there is a lack of valid information provided to mothers on cardiotocography, interpretation of CTG records and their relevance. This hypothesis was confirmed by the research. The women{\crq}s in childbed attitude toward cardiotocographical fetal monitoring during childbirth was evaluated and thus objectives of the thesis were met. Holistic approach in nursing care is supposed to ensure that all patients have access to the best possible comfort, comprehensive care and enough information. The conclusions of the research conducted in the Gynecological-Obstetrical clinic imply the need to improve communication and the flow of information from medical staff to women in childbed and technical possibility of CTG recorders.
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