National Repository of Grey Literature 12 records found  previous11 - 12  jump to record: Search took 0.00 seconds. 
Computational modelling of heart contraction
Vaverka, Jiří ; Polzer, Stanislav (referee) ; Burša, Jiří (advisor)
This thesis aims to determine the impact of slowed myocardial conduction velocity and depressed myocyte contractility on the duration of isovolumic contraction time (ICT) of the left ventricle by carrying out simulations using finite element method. A 3D finite element model enabling to simulate both physiological and pathological states of myocardium was created. The model is based on simplified ellipsoidal geometry and accounts for anisotropic behavior of myocardium, its asynchronous contraction and variations in the arrangement of muscle fibers. Slowing of conduction velocity to a half of its physiological value resulted in prolongation of ICT by 27 %; slowing of shortening velocity of myocytes by the same percentage prolonged ICT by 73 %. It is therefore concluded that ICT can be much more prolonged due to depressed contractility than due to conduction slowing. The presented results give an idea of the extent to which ICT can be prolonged due to depressed contractility and conduction slowing and therefore can be useful in identifying the causes of decreased myocardial performance in heart disease.
Expert System for Detection of Ventricular Extrasystoles
Svánovská, Zuzana ; Mézl, Martin (referee) ; Sekora, Jiří (advisor)
Ventricular premature beats are ectopic changes in the ECG signal. Detection of ventricular extrasystoles on 12leads ECG was created in MATLAB. At first my work involves whether the ventricular premature beats comes from the right or the left ventricle. Another algorithm evaluates the incidence outflow tract of the chamber. If the previous algorithm shows signs of indecision, another algorithm is used for detection of ventricular extrasystoles at another location in the left ventricle. The last step is to narrow the area of detection which makes it easier to find the place of origin.

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