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National Repository of Grey Literature

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Pharmacoeconomics from the point of view of the interest groups Pohlová, Martina ; Maaytová, Alena (advisor) ; Hartlová, Alena (referee) This thesis deals with pharmacoeconomics and its application from the interest groups' active in the health care system point of view. Pharmacoeconomics is a relatively new scientific discipline, whose purpose is to facilitate the efficient allocation of scarce resources in the health care sector. The first chapter analyzes the trend of expenditure on health of the Czech Republic. The second chapter describes the question of pharmacoeconomic research. The third chapter discusses possible ways to use pharmacoeconomics by the interest groups. Detailed record

Cost-effectiveness analysis of sequential therapy of depression Šóš, Peter ; Lešetický, Ondřej (advisor) ; Novák, Tomáš (referee) Applying pharmacoeconomic methods were compared two selected treatments of depressive disorder. Markov model was created to evaluate cost-effectiveness of the two strategies. Knowledge from the clinical practice and the clinical research findings of the author are linked with pharmacoeconomic techniques into a multidisciplinary complex. The proposed sequential therapy uses a prediction of antidepressant response by utilizing of recent quantitative electroencephalography methods. Sequential therapy is more cost-effective compared with the conventional therapeutic strategy according to clinical guidelines. The results and limitations of the study are discussed at the conclusion from clinical and economic perspective. Detailed record

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