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National Repository of Grey Literature

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Spliceosomal Assembly on Precursor mRNA Takes Place in the Nuclear Speckles Melčák, Ivo ; Cermanová, Štěpánka ; Raška, Ivan Nuclear speckles (speckles), enriched in splicing factors, form a distict nuclear compartment within the interchromatin space. It has been schown to serve vicinal active genes as a reservoir of splicing factors.We show that (pre-)spliceosomal assemblyy on pre-mRNA is associated with the speckles in HeLa cells. Detailed record

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