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National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Remodelace živé kosti – numerická simulace
 Klika, V. ; Maršík, František ; Barsa, P.
The capacity of bone to adapt to functional mechanical requirements has been known for more than a century, and many theoretical and experimental models have been developed for bone remodelling. However, these models are still not able to sufficiently predict its behaviour. A thermodynamic model based on recent knowledge of biochemical control mechanisms is presented. Despite the complexity of the regulatory system of bone adaptation, the calculated results are in very good correlation with the experimental observations - the inner structure of bone can be elucidated, simulation of the influence of dynamic loading together with biochemical factors, e.g. the fundamental RAKL-RANK-OPG pathway.
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