|
|
Plasmachemical preparation of polymer layers based on 2-ethyl-2-oxazoline and their diagnostics
Podzemná, Erika ; Menčík, Přemysl (referee) ; Mazánková, Věra (advisor)
The bachelor’s thesis deals with deposition of thin polymer layers on 2-ethyl-2-oxazolin basis in a dielectric barrier discharge in a nitrogen atmosphere. Polyoxazolines are characterized by good antibacterial effects in general, which make them a suitable material for medical applications. After preparing of the layers. Their properties were studied using three methods. The first were antibacterial tests, which unfortunately did not confirm the above written properties. Furthermore, the free surface energy of the layers, from which it could be inferred that the surfaces were hydrophilic, was determined by measuring contact angles. The scanning electron microscopy showed the surface of the layers as well as the elemental composition thanks to the connected X-ray detector.
|
|
|
Plasma chemical deposition of thin polymer layers based on 2-ethyl-2-oxazoline and their diagnostics
Podzemná, Erika ; Horák, Jakub (referee) ; Mazánková, Věra (advisor)
Medical devices are often subject to the colonisation of bacteria, making it a prerequisite for infection in the patient's body. To prevent biofilm, the medical device can be covered with a thin layer of polymeric substance that has the ability to prevent biological fouling. In this work, was selected 2-ethyl-2-oxazoline as a precursor for the formation of thin polymer layers. In general, the oxazoline group is known for its antibacterial and biocompatible properties, which is the reason for choosing this substance. The main objective of this thesis was the deposition of thin polymer films, which are based on 2-ethyl-2-oxazoline, in surface dielectric barrier discharge under atmospheric pressure. The principle of thin layer formation on a teflon substrate is plasma polymerization. The preparation of the layers was followed by their characterization by several methods. Their physical and chemical properties were studied using SEM, FTIR, and by measuring the contact angles of the surface of the layers. Furthermore, the processes that take place in plasma, when there is an interaction of electrons and ions with the monomer molecule, were investigated. Ion mobility spectrometry and the crossed-beam ionization method were used for this measurement. The layers were also tested for their antibacterial and cytocompatible properties.
|
|
|
Plasmachemical preparation of polymer layers based on 2-ethyl-2-oxazoline and their diagnostics
Podzemná, Erika ; Menčík, Přemysl (referee) ; Mazánková, Věra (advisor)
The bachelor’s thesis deals with deposition of thin polymer layers on 2-ethyl-2-oxazolin basis in a dielectric barrier discharge in a nitrogen atmosphere. Polyoxazolines are characterized by good antibacterial effects in general, which make them a suitable material for medical applications. After preparing of the layers. Their properties were studied using three methods. The first were antibacterial tests, which unfortunately did not confirm the above written properties. Furthermore, the free surface energy of the layers, from which it could be inferred that the surfaces were hydrophilic, was determined by measuring contact angles. The scanning electron microscopy showed the surface of the layers as well as the elemental composition thanks to the connected X-ray detector.
|
guest ::
