Národní úložiště šedé literatury Nalezeno 4 záznamů.  Hledání trvalo 0.00 vteřin. 
Effect of Thymine and Cytosine Nucleobase Sequence on the Two-Dimensional Condensation of Pyrimidine Oligodeoxynucleotides at Mercury Surface
Hasoň, Stanislav ; Fojta, Miroslav
The aim of this contribution is study the effect of thymine and cytosine nucleobase composition (different lengths and/or repeat segments of either thymine or cytosine units or their combinations) within a set of the oligodeoxynucleotide (ODN) chains on the two-dimensional of homo- and hetero-pyrimidine ODNs at mercury electrode surface. It was shown that pyrimidine ODNs containing eight and more pyrimidine nucleobases can form, at negatively charged Hg surface (around1.32 V vs. Ag/AgCl), two different 2D condensed films characterized by the differential capacitances of about 9.4 (I-2D) and 7.6 mu F cm(-2) (II2D) respectively.
Reduction of the DNA at a Pyrolytic Graphite Electrode:Opening of the Second Half of the Potential Window
Špaček, Jan ; Daňhel, Aleš ; Hasoň, Stanislav ; Hejduková, M. ; Fojta, Miroslav
The pyrolytic graphite electrode (PGE) can be used at highly negative potentials, providing reduction signals known from mercury-based electrodes. Use of the negative part of the potential window more than doubled the number of analytically useful signals provided by unlabelled DNA on PGE. It enables selective analysis of all canonical DNA bases,5-methylcytosine and uracil It also allows for distinction of overlapping signals cathodic polarization can selectively ´switch off´ DNA anodic signals and rice versa. Newly observed signals corresponding to oxidation of reduced bases and reduction of oxidized bases are also described.
Voltammetric Detection of Purine Nucleobases on Screen-Printed Graphite Electrodes Modified by Nanocarbon Materials
Hasoň, Stanislav ; Ostatná, Veronika ; Fojta, Miroslav
Recent studies have shown that the electrochemical oxidation of purine nucleobases (adenine and geaoine) at graphite electrodes is strongly dependent on the orientation of graphene sheets. their size and mutual distribution on the electrode surface. Edges and defects of graphene sheets affect the kinetics of oxidation processes, basal planes support the adsorption processes The aim of this study is to determine how model carbon nanomaterials including graphene, single-walled or multi-wailed carbon nanotubes. carbon nanofibres and mesoporous graphene affect the electrochemical oxidation or purine nuclebases on screen-printed carbon electrodes modified by these nanostructures in solution without and in the presence of copper.
Impedance measurements of nucleic acids and self-assembled layers of their components
Vetterl, Vladimír ; Jelen, František ; Dražan, Viktor ; Strašák, Luděk ; Hasoň, Stanislav ; Dvořák, Jakub
The kinetics of structural changes of cytidine adlayers on the mercury electrodes were investigated by means of current and capacitance transients using the potential step technique.

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1 Hasoň, S.
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