National Repository of Grey Literature 35 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
Immunoregulatory characteristics of immune cells of children of allergic and non-allergic mothers and the possibility of their modulation with probiotic E.coli O83:K24:H31
Černý, Viktor
Due to high incidence, medical and socioeconomic burden and impact on individual quality of life and productivity, allergic disorders are a crucial issue for 21st century immunology. Much still remains to be elucidated, particularly regarding the very early processes in allergy development. In order to introduce timely, effective preventive measures, novel, more reliable predictive factors of allergy risk also need to be established. Dysregulation of proper balance between the branches of immune response, particularly unwarranted dominance of Th2, is the underlying cause of allergy. After birth, new immune balance needs to be established to prepare the neonate for adequate reactivity towards newly encountered environmental stimuli. Regulatory T cells (Treg) play a central role in finely setting this balance and inducing tolerance towards harmless environmental antigens, including allergens. Interactions with external factors, most importantly microbiota, modulate this process during the early postnatal "window of opportunity." Analysis of cord blood Treg of children of allergic mothers uncovered decreased presence of function-associated surface markers and lower production of IL-10. Furthermore, decreased proportion of Helios- induced Treg was observed in children with higher risk of allergy....
Population structure, migration and dynamics in Africa and Arabia
Čížková, Martina ; Černý, Viktor (advisor) ; Frynta, Daniel (referee) ; Zrzavý, Jan (referee)
In addition to the interaction of evolutionary forces, the population history of the African Sahel and Arabia has been influenced by the spread of Neolithic cultural innovations. The reflection of these processes today is a very complex structured diversity of the current populations, which is presented here through the analysis of several genetic markers. The aim is to provide a comprehensive view of the history of demographic processes in the Sahel and Arabia, by combining genetic, linguistic, subsistence and geographical data obtained from local populations. A study of a large dataset of mtDNA sequences showed that Arabia was a major crossroads in gene flow, and although it was colonized by anatomically modern humans from East Africa, today's differentiation from Africa is greater than the differentiation between local populations in these regions. Even the Sahel was an important biocorridor in the past. Today, we encounter populations of various subsistence strategies (nomadic pastoralists and settled farmers), between which gene flow has been severely restricted. A comparison of uniparently inherited loci in both groups points to different migratory activity in the eastern and western parts of the Sahel. Analyzes of Alu elements, which indicated the inclination of West African herders (Fulbs)...
Software for audio adjustment in multiple loudspeaker system
Černý, Viktor ; Schimmel, Jiří (referee) ; Sysel, Petr (advisor)
The first part of this Master’s Thesis deals with the theory of digital signal processing and describes the JUCE library. In this part some basic operations are explained with digital audio signals, such as polarity inversion, delay and linear interpolation of signal samples. The creation of new audio applications using the JUCE library in the C++ programming language is explained too. The next parts of this thesis describe the implemented audio application that allows the user to provide the described basic operations with digital audio signals in real time. For multiple channel audio signals the channels can be processed independently.
Immunoregulatory characteristics of immune cells of children of allergic and non-allergic mothers and the possibility of their modulation with probiotic E. coli strain O83:K24:H31
Černý, Viktor ; Hrdý, Jiří (advisor) ; Tlaskalová - Hogenová, Helena (referee) ; Černá, Marie (referee)
Due to high incidence, medical and socioeconomic burden and impact on individual quality of life and productivity, allergic disorders are a crucial issue for 21st century immunology. Much still remains to be elucidated, particularly regarding the very early processes in allergy development. In order to introduce timely, effective preventive measures, novel, more reliable predictive factors of allergy risk also need to be established. Dysregulation of proper balance between the branches of immune response, particularly unwarranted dominance of Th2, is the underlying cause of allergy. After birth, new immune balance needs to be established to prepare the neonate for adequate reactivity towards newly encountered environmental stimuli. Regulatory T cells (Treg) play a central role in finely setting this balance and inducing tolerance towards harmless environmental antigens, including allergens. Interactions with external factors, most importantly microbiota, modulate this process during the early postnatal "window of opportunity." Analysis of cord blood Treg of children of allergic mothers uncovered decreased presence of function-associated surface markers and lower production of IL-10. Furthermore, decreased proportion of Helios- induced Treg was observed in children with higher risk of allergy....
Y-chromosomal polymorphisms in the Czech population with focus on Moravian Valachs: evolutionary anthropology study.
Ehler, Edvard ; Vančata, Václav (advisor) ; Černý, Viktor (referee) ; Brdička, Radim (referee)
1 Abstract Aim: This study presents an evolutionary anthropology approach to the history of Moravian Valachs. The origins of Valach population are approached by evaluating the admixture event that marked the appearance of Moravian Valachs. Methods & data: Focus of my Ph.D. project lies on Y-chromosomal variation, using 12 Y-STR loci haplotype to compute population genetic statistics, to infer Y-chromosomal haplogroup information and to compare Moravian Valachs to other European populations. Admixture analysis was performed. Our data set contains haplotypic information from 44 populations with the total of 4757 individuals. Moravian Valachs are presented by 94 DNA samples. Results: Our data reveal a decreased genetic variability in Moravian Valachs compared to other Central European populations. This feature is most probably caused by isolation of Valach population. Multidimensional scaling and comparison of FST distances shows Valach population as related to populations from Poland, Romania and Macedonia. Shared haplotypes and AMOVA tests place the Valachs to the Central European region. Also admixture analysis, as well as demographic and historical data, stresses the influence of autochthonous population of Moravia in the forming of Moravian Valachs. Conclusion: Moravian Valachs represent a hybrid...
Tool for subjective quality evaluation of audiosignals restoration
Černý, Viktor ; Dorazil, Jan (referee) ; Záviška, Pavel (advisor)
Bacherol thesis deals with the theory of audio signal depreciation and reconstruction, with objective tests and subjective methods of reconstructed signal evaluation. At first, there are described several types of depreciation of audio signals and then reconstruction types for their reconstruction. After the reconstruction, types six objective and six subjective tests are mentioned for the evaluation of audio signal quality. The next part of the Bachelor thesis is the description of the program that was implemented in the programming language Java. The program is designed to design MOS, MUSHRA and ABX listening tests as well as to use for the actual testing. At the end of the thesis are the results of the listening tests that were used to test the program and the user ratings of the application.
Sequence diversity of mtDNA and genetic structure of eastern part of the African Sahel
Tlačbabová, Klára ; Černý, Viktor (advisor) ; Munclinger, Pavel (referee)
Eastern part of the African Sahel, connecting sub-Saharan Africa with North and East Africa, play an important role as a bidirectional corridor for vertically and horizontally migrations of populations. It is the strategic region to study human genetic diversity due to the presence of ethnically, linguistically, culturally and geographically diversity. This work is focused on the analysis of HVS-I and HVS-II segments of mtDNA. The work provides new information about genetic structure and migration activity of this region by analysis twelve populations belonging to three African linguistic families and different subsistent strategies. Analysis of mtDNA revealed the higher diversity of the populations of east Sudan and Horn of Africa, which is connected with the spreading of populations along the Nile River. It seems, that in this region linguistic factors have bigger impact on genetic diversity then the geografic ones. The opposite situation is observed in populations of Chad, where populations with similiar geografic location and different linguistic affilation revealed low genetic differentiation. The intra-population analysis shows the significant influence of genetic drift on the pastoralists living on the Red Sea Coast - Beja and Rashaida. In Beja is probably due to decrease of size of...
Cattle Domestication and pastoralism in the African Sahel
Salajková, Veronika ; Černý, Viktor (advisor) ; Kyselý, René (referee)
Breeding of domesticated animals was one of the most important events which led to a significant progress in the history of mankind. Domestication appeared in several places simultaneously and inhabitants of these areas gained a considerable advantage in comparison with their hunters- gatherers ancestors. Fertile Crescent in the Near East, where many useful animals were domesticated, cattle included, was most important of them. In sub-Saharan territory gradual introduction of pastoral farming was limited for example by incidence of serious diseases in certain areas. In addition, Sahara, which in the past used to be a very favourable pastoral territory, in the progress of time started to change into despairing desert and the onset of devastating drought forced local inhabitants to move to the area of Sahel and to engage with cattle breeding. Due to the reduction of other natural sources local inhabitants had to draw attention to milk production which became an important source of food. Some of them have not left this life strategy up to the present time.

National Repository of Grey Literature : 35 records found   1 - 10nextend  jump to record:
See also: similar author names
10 ČERNÝ, Vojtěch
4 ČERNÝ, Václav
1 Černý, V.
14 Černý, Vladimír
1 Černý, Vlastimil
10 Černý, Vojtěch
4 Černý, Václav
5 Černý, Vít
3 Černý, Vítězslav
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