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Aktuální molekulární polymorfizmy genů a molekulární metody analýzy kvality masa u masných plemen skotu
 Venusová, Eva
Due to increasing demand for quality from costumers also grows up demand for superior meat. On meat quality takes part great number of genes together with outer environment. Thus, goal of my bachelors thesis is to describe polymorphisms and candidate genes associated with cattle focused for meat yield. In this thesis are described candidate genes for marbling in which belongs genes DGAT1, thyroglobulin and leptin where have been proofed an influence on amount of intramuscular fat in meat. In scope of meat tenderness were further described genes CAST and CAPN1. Other genes associated with on growth of muscle fibers and muscle amount of cattle are of MYOD family, IGF family and gene MSTN. In terms of the topic of bachelors thesis are also mentioned molecular methods analyses and selection methods which serves for detection of suitable candidate genes and their polymorphisms influencing quality of cattle meat.
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Využití elektrochemických technik pro studium apoferritinu
 Venusová, Eva
Theme of this diploma thesis is usage of electrochemical techniques for study of apoferritin, which is artificially synthetized protein derived from ferritin. Apoferritin has empty cavity which can be used for completion of broad amount of substances. Encapsulation of anticancer drugs can decrease their unwanted side effects such as strong toxicity and therefore increase it’s effectiveness at the tumor site. Substances chosen in this diploma thesis were standard platinum and platinum drugs cisplatin and it’s analogy oxaliplatin. Measurement was performed by electrochemical method differential pulse voltammetry by which was determined encapsulation capacity of apoferritin for chosen anticancer drugs. For determination size and zeta potential of nanoparticles was used colloid analyzator ZetaSizer Nano.
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