National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Pyrazine derivatives as potential drugs VI.
Servusová, Barbora ; Doležal, Martin (advisor) ; Opletalová, Veronika (referee)
Title of diploma thesis: Pyrazine derivates as potential drugs VI. Review of tuberculosis therapy and modern research were presented in this diploma thesis. Six novel compounds substituted anilides pyrazine-2-carboxylic acid character were synthesized. Products were characterized by melting points, TLC, IR, 1 H and 13 C NMR. This set was put through in vitro biological evaluation. Log P and Clog P were also calculated. These values were put into the structure-activity relationships of prepared compounds.
Pyrazine derivatives as potential drugs VI.
Servusová, Barbora ; Doležal, Martin (advisor) ; Opletalová, Veronika (referee)
Title of diploma thesis: Pyrazine derivates as potential drugs VI. Review of tuberculosis therapy and modern research were presented in this diploma thesis. Six novel compounds substituted anilides pyrazine-2-carboxylic acid character were synthesized. Products were characterized by melting points, TLC, IR, 1 H and 13 C NMR. This set was put through in vitro biological evaluation. Log P and Clog P were also calculated. These values were put into the structure-activity relationships of prepared compounds.

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