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Léčba autoimunitních onemocnění helmintoterapií
 STRANKMÜLLEROVÁ, Zuzana
This bachelor thesis will discuss the impact of gastrointestinal helminths on the human immune system concentrating especially on their therapeutical potency in the treatment of autoimmune diseases. Epidemiological studies show a significant difference between developing and developed countries. This inequality gave rise to the two hypotheses: the Hygiene Hypothesis and the Old Friend Hypothesis. These theories mention the fact that exposure to the parasites may lower the risk of developing autoimmune diseases. Anti-inflammatory products of helminths modulate the immune system to induce Th2 response (with rising levels of anti-inflammatory cytokines e.g. IL-4, IL-10 a TGF-). Therefore, helminths or their molecules can cure autoimmune inflammatory diseases or even diseases of civilisation.
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