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Nanomaterials based on nano-ion hydrophylic polymer interactions
Mesíková, Soňa ; Matějíček, Pavel (advisor) ; Strachota, Adam (referee)
The Thesis deals with the co-assembly of triblock copolymers poly(2-(N, N, N′, N′-tetramethyl guanidinium)ethyl acrylate)-b-poly(ethylene oxide)-b-poly(2-(N, N, N′, N′-tetramethyl guanidinium)ethyl acrylate), PGEA-PEO-PGEA, and poly(N-isopropylacrylamide)-b- poly(acrylic acid)-b-poly(N-isopropylacrylamide), PNIPAM-PAA-PNIPAM, with anionic boron cluster compounds closo-dodecaborate anion, [B12H12]2- , and [cobalt(3+) bis(1,2- dicarbollide)] anion, COSAN, in aqueous solutions, respectively. Synthesis of PNIPAM-PAA- PNIPAM triblock copolymers was performed. The formation of gels based on electrostatic interactions of cationic blocks of PGEA-PEO-PGEA copolymer with closo-dodecaborate anion and on dihydrogen bonding of neutral PNIPAM blocks of PNIPAM-PEO-PNIPAM with COSAN was investigated. The inner structure of the gels was investigated by scattering techniques and fluorescent spectroscopy. Their mechanical properties were studied by diverse rheology measurements. Influence of lithium and sodium salts on PEO/COSAN complex formation and stability in aqueous solution was also studied.
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Preparation of hybrid nanoparticles based on interaction of block polyelectrolytes with atypical ions
Mesíková, Soňa ; Matějíček, Pavel (advisor) ; Štěpánek, Miroslav (referee)
The Thesis deals with the co-assembly behaviour of cationic diblock copolymers poly(2- vinyl pyridine)-b-poly(ethylene oxide), P2VP-b-PEO, and poly(ethylene oxide)-b-poly(2- (N, N, N′, N′-tetramethyl guanidinium) ethyl acrylate), PEO-b-PGEA, with closo- dodecaborate anion, [B12H12]2- , in aqueous solutions. Formation of stable PEO-b- PGEA/[B12H12] nanoparticles was investigated by static and dynamic light scattering and 1 H NMR spectroscopy, and they were visualized as spherical nanoparticles by cryo- TEM imaging. According to the NMR results, both studied diblock copolymers form core- corona micelles with dodecaborate. The micellar molar mass and the aggregation number of PEO-b-PGEA/[B12H12] micelles were obtained in water and 0.156 M NaCl solution by standard Zimm method. For this, refractive index increment was evaluated by refractometer. The studied nanoparticles are promising for the boron delivery in medicine.
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Preparation of hybrid nanoparticles based on interaction of block polyelectrolytes with atypical ions
Mesíková, Soňa ; Matějíček, Pavel (advisor) ; Štěpánek, Miroslav (referee)
The Thesis deals with the co-assembly behaviour of cationic diblock copolymers poly(2- vinyl pyridine)-b-poly(ethylene oxide), P2VP-b-PEO, and poly(ethylene oxide)-b-poly(2- (N, N, N′, N′-tetramethyl guanidinium) ethyl acrylate), PEO-b-PGEA, with closo- dodecaborate anion, [B12H12]2- , in aqueous solutions. Formation of stable PEO-b- PGEA/[B12H12] nanoparticles was investigated by static and dynamic light scattering and 1 H NMR spectroscopy, and they were visualized as spherical nanoparticles by cryo- TEM imaging. According to the NMR results, both studied diblock copolymers form core- corona micelles with dodecaborate. The micellar molar mass and the aggregation number of PEO-b-PGEA/[B12H12] micelles were obtained in water and 0.156 M NaCl solution by standard Zimm method. For this, refractive index increment was evaluated by refractometer. The studied nanoparticles are promising for the boron delivery in medicine.
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