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The role of monoamines in the immune system regulation during infection
Matajová, Kamila ; Voukali, Eleni (advisor) ; Porubská, Bianka (referee)
Monoamines (norepinephrine, epinephrine, dopamine, serotonin, melatonin and histamine) have been extensively studied for their ability to regulate the activity of the immune system during infection in mammals and birds. Monoamines can induce a response in immune cells through their receptors and on the other hand, immune cells can affect the central nervous system through the release of cytokines. The effect on the immune system mediated by monoamines is stimulatory or inhibitory, tuned for the appropriate immune response to ensure a higher probability of the animal survival. Any weakening of this interaction leads to impaired immune function or deficient development of immune organs. Keywords: monoamines, immune system, infection, mammals, birds
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The role of monoamines in the immune system regulation during infection
Matajová, Kamila ; Voukali, Eleni (advisor) ; Porubská, Bianka (referee)
Monoamines (norepinephrine, epinephrine, dopamine, serotonin, melatonin and histamine) have been extensively studied for their ability to regulate the activity of the immune system during infection in mammals and birds. Monoamines can induce a response in immune cells through their receptors and on the other hand, immune cells can affect the central nervous system through the release of cytokines. The effect on the immune system mediated by monoamines is stimulatory or inhibitory, tuned for the appropriate immune response to ensure a higher probability of the animal survival. Any weakening of this interaction leads to impaired immune function or deficient development of immune organs. Keywords: monoamines, immune system, infection, mammals, birds
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