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Evaluation of flavonoids content in various species of Bergenia genus
Marková, Almíra ; Tůmová, Lenka (advisor) ; Karlíčková, Jana (referee)
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmacognosy and Pharmaceutical Botany Author: Almíra Marková Supervisor: Assoc. Prof. PharmDr. Lenka Tůmová, CSc. Title of diploma thesis: Evaluation of flavonoids content in various species of Bergenia genus Originally an Asian genus Bergenia from the family Saxifragaceae includes 32 species described so far and many hybrids that were created by crossing them. The leaves and rhizomes of bergenia used widely in folk medicine of China, India, Mongolia, and Russia are rich in a wide range of chemical constituents. The most important secondary metabolites of this plant are tannins, arbutin, bergenin, but also flavonoids. The drug is valued for its litholytic, antioxidant, anti-inflammatory, antipyretic, or antitussive properties. This work aimed to determine flavonoid content in red and green leaves of Bergenia crassifolia (L.) Fritsch, Bergenia ciliata (Haw.) Sternb. and Bergenia x ornata Guill. and their comparison with each other depending on the harvest period and climatic conditions. The samples were obtained from the botanical garden of the Faculty of Horticulture of Mendel University in Lednice. Flavonoid content was determined spectrophotometrically. The highest flavonoid content was measured in B. ciliata (1.1829 ±...
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