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An algorithm of the pre-hospital and the acute hospital care during an ethylene glycol intoxication.
MILOTA, Jiří
Ethylene glycol intoxication is a serious life threatening condition, that may appear to be a serious risk in connection with the easy availability of preparations containing this substance. The work titled An algorithm of the pre-hospital and the acute hospital care during an ethylene glycol intoxication provides information on this issue and summarizes appropriate treatment in pre hospital and acute hospital care, which should lead to increased treatment efficiency and reduced health consequences. The most common source of ethylene glycol in the household is anti freeze mixtures for vehicles, the most often accidental ingested liquid. The toxic nature of ethylene glycol is a decomposition into acidic metabolites and formation of calcium crystals causing necrosis and organ failure. A typical immage of ethylenglycol intoxication is a consciousness depresion, total acidosis, acute renal failure, and an increased anion gap. Appropriate therapy should be initiate by first aid, followed by professional pre hospital and hospital care. There should be made a gastric decontamination in first houre of ingestion. Vital functions must be provided, but the key method is using of antidotes (alcohol dehydrogenase inhibitors ethanol or fomepizol). In case of indikation causal treatment also includes elimination methods, most often intermittent hemodialysis and cofactor application. Symptomatic treatment is based on acid base homeostasis and specific biochemical levels balance. The thesis was made by form of review and synthesis using large number of science sourc es dealing with the current issue of EG intoxication. The main purpose of work is comparing of Czech and global authors to illustrate different possibilities of treatmet and create educational material for students of health care disciplines or medical professionals looking for quick and simply way to solve acute emergency or crate an idea of adequate care.
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