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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Ovine hemonchosis-results of its laboratory control in course of experimental infection
 Lochmanová, Eva ; Lamka, Jiří (advisor) ; Ducháček, Lubomír (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Lochmanová Eva Supervisor: prof. RNDr. Jiří Lamka, CSc. Title of diploma thesis: Ovine hemonchosis - results of its laboratory control in course of experimental infection The anthelmintic resistance is a matter of interest in many professional workplaces, as it creates high losses for practical farm animals breeding and it represents a potentially limiting factor for the existence of their own holdings. The mechanisms leading to the anthelmintic resistance emergence are studied, and among them there is also the possibility of induction of biotransformation enzymes, that the parasites (round worms) use to overcome the contact with what is xenobiotics for themselves. Parasitic models and in the long term also Haemonchus contortus are used. Three strains of the parasite are used in the Department of Biochemical Sciences Faculty of Pharmacy, Charles University in Hradec Kralove: fully susceptible, fully resistant, resistant only to benzimidazole anthelmintics. Parasites are experimentally reared in sheep. The aim of this thesis was to experimentally document parasitoses experimental course all of these strains by parasitological methods. L3 larvae Haemonchus contortus were given to...
Detailed record
Ovine hemonchosis-results of its laboratory control in course of experimental infection
 Lochmanová, Eva ; Lamka, Jiří (advisor) ; Ducháček, Lubomír (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Lochmanová Eva Supervisor: prof. RNDr. Jiří Lamka, CSc. Title of diploma thesis: Ovine hemonchosis - results of its laboratory control in course of experimental infection The anthelmintic resistance is a matter of interest in many professional workplaces, as it creates high losses for practical farm animals breeding and it represents a potentially limiting factor for the existence of their own holdings. The mechanisms leading to the anthelmintic resistance emergence are studied, and among them there is also the possibility of induction of biotransformation enzymes, that the parasites (round worms) use to overcome the contact with what is xenobiotics for themselves. Parasitic models and in the long term also Haemonchus contortus are used. Three strains of the parasite are used in the Department of Biochemical Sciences Faculty of Pharmacy, Charles University in Hradec Kralove: fully susceptible, fully resistant, resistant only to benzimidazole anthelmintics. Parasites are experimentally reared in sheep. The aim of this thesis was to experimentally document parasitoses experimental course all of these strains by parasitological methods. L3 larvae Haemonchus contortus were given to...
Detailed record

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