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National Repository of Grey Literature

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Účinek antimikrobiálních prostředků na mikroorganismy dutiny ústní Kudiyirickal, Marina George ; Koberová Ivančaková, Romana (advisor) ; Hamal, Petr (referee) ; Poleník, Pavel (referee) Disease of the pulp and periodontium which constitute the vast proportion of odontogenic infections are mainly caused by the endogenous bacterial microbiota in the oral cavity while non odontogenic infections in the same area vary depending on the nature and site of infection. The rational use of antibiotic is important to prevent development of resistant strains and other side effects of drugs. Aim: To investigate (i) the prevalence of bacterial species in oral samples of patients with bacterial infection reporting at the Dept of Dentistry (1996- 2007), (ii) to assess the age and sex predilection and , (iii) and species specific relationships, and (iv) to determine the susceptible-resistant biotype profile of the bacterial isolates from odontogenic and non odontogenic infections. Materials and methods: Laboratory and clinical data of patient's electronic files at Dept of Microbiology, Faculty of Medicine and Teaching Hospital in Hradec Králové for the years 1996-2007 were evaluated retrospectively. Results: Bacterial orofacial odontogenic or non odontogenic infection was detected in a total of 678 patients with 350 males (51.6%) and 328 females (48.4%). The bacterial isolates included 48 bacterial species with predominance of facultative anaerobes which accounted for 78.5% (n= 1263) and obligate anaerobes... Detailed record

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