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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Determination of 6-sulfatoxymelatonin by capillary electrophoresis
 Klimánková, Karla ; Jezberová, Michaela (advisor) ; Polášek, Miroslav (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biophysics and Physical Chemistry Candidate Mgr. Karla Klimánková Consultant RNDr. Michaela Hamerníková, Ph.D. Title of Thesis Determination of 6-sulfatoxymelatonine by Capillary Electrophoresis The submited thesis deals with a development of a method for determination of 6-sulfatoxymelatonine for purposes of the gerontological research. Parameters of the electrophoretic determination were optimized, i. e.: composition of the base electrolyte, its pH, voltage, time of injection. Then folloving validation parameters were determined: linearity, repeatability, reproducibility of migration times and limit of detection. The obtained results confirm the applicability of the method for the given purpose.
Detailed record
Determination of 6-sulfatoxymelatonin by capillary electrophoresis
 Klimánková, Karla ; Jezberová, Michaela (advisor) ; Polášek, Miroslav (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biophysics and Physical Chemistry Candidate Mgr. Karla Klimánková Consultant RNDr. Michaela Hamerníková, Ph.D. Title of Thesis Determination of 6-sulfatoxymelatonine by Capillary Electrophoresis The submited thesis deals with a development of a method for determination of 6-sulfatoxymelatonine for purposes of the gerontological research. Parameters of the electrophoretic determination were optimized, i. e.: composition of the base electrolyte, its pH, voltage, time of injection. Then folloving validation parameters were determined: linearity, repeatability, reproducibility of migration times and limit of detection. The obtained results confirm the applicability of the method for the given purpose.
Detailed record

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