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The Comparison of Personal Income Tax in the Czech Republic and Republic of Ireland
Obertíková, Sandra ; Krejčová, Hana (referee) ; Kopřiva, Jan (advisor)
The Thesis focuses on a comparison of taxation of individuals in the Czech Republic and in the Republic of Ireland. The Thesis construes a issue of taxation of self-employed and their process of taxation on the examples. In conclusion of this Thesis are tax optimization suggestions for taxpayer. Above that is includes Convention between the Czech Republic and the Republic of Ireland for the avoidance of double taxation and the prevention of fiscal evasion with respect to taxes on income and on capital.
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Veřejné zakázky a bid rigging
Krejčová, Hana
The Diploma thesis deals with the public procurement issue and the bid rigging. The first part of this thesis is focused theoretically on related legislation of public procurement in the Czech Republic. Herein are in this thesis defined public pro-curements and their types, role of contracting authority and award procedure. The further chapter is devoted to the bid rigging and to its theoretical background. The second part of thesis analyses decisions of the case law of bid rigging, influence of the bid rigging. Furthermore, there are suggested the possible results of detection and prevention of bid rigging.
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Transdermal in vitro permeation of cyclosporine. III.
Krejčová, Hana ; Doležal, Pavel (advisor) ; Zbytovská, Jarmila (referee)
Diploma Thesis, Hana Krejčová 2006 Abstract The theoretical part of thesis provides a brief overview of the transdermal administration of drugs, including the use of transdermal enhancer. Part concerning the CyA includes information about its structure, pharmacological effects, including adverse effects, its use in therapy and application possibilities. Experimental section presents the results of in vitro permeation experiments on pig skin. Acceptor phase consisted of propylene glycol and Tris-buffer pH 7.1 at a 1:1 ratio. The permeant determination was performed by HPLC with UV detection at 220 nm. It was confirmed that the choice of the acceptor and the mobile phase was appropriate. As a donor samples were used supersaturated CyA systems without enhancer, and also with the addition of 5% or Azone, methyl pyrrolidone or dodecyl pyrrolidone, or 1% of transkarbam 12. All the enhancers in the concentrations increase depot formation in skin, transkarbam 12 although used in the lowest concentration did it most.
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Transdermal in vitro permeation of cyclosporine. III.
Krejčová, Hana ; Doležal, Pavel (advisor) ; Zbytovská, Jarmila (referee)
Diploma Thesis, Hana Krejčová 2006 Abstract The theoretical part of thesis provides a brief overview of the transdermal administration of drugs, including the use of transdermal enhancer. Part concerning the CyA includes information about its structure, pharmacological effects, including adverse effects, its use in therapy and application possibilities. Experimental section presents the results of in vitro permeation experiments on pig skin. Acceptor phase consisted of propylene glycol and Tris-buffer pH 7.1 at a 1:1 ratio. The permeant determination was performed by HPLC with UV detection at 220 nm. It was confirmed that the choice of the acceptor and the mobile phase was appropriate. As a donor samples were used supersaturated CyA systems without enhancer, and also with the addition of 5% or Azone, methyl pyrrolidone or dodecyl pyrrolidone, or 1% of transkarbam 12. All the enhancers in the concentrations increase depot formation in skin, transkarbam 12 although used in the lowest concentration did it most.
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Transdermal in vitro permeation of cyclosporine IV.
Krejčová, Hana ; Doležal, Pavel (advisor) ; Musilová, Marie (referee)
Rigorosal Thesis 2006, Hana Krejčová Abstract The theoretical section gives a brief overview of anatomy, physiology and function of the skin, transdermal formulations and options for increasing transdermal absorption of drugs. The main part of the chapter is focused on cyclosporine includes updated information published on knowledge of the human immune system, and immunosuppressants. Experimental work presents the results of in vitro permeation experiments on pig skin. Donor and acceptor phase was in most experiments consisting propylene glycol and Tris-buffer pH 7.1 at a 1:1 ratio. Only a few experiments have been used as the donor phase of 10% dispersion of CyA in isopropylmyristate. Permeant determination was performed by HPLC with UV detection at 220nm. As a donor samples were used in the supersaturated system without CyA Enhancer, then a 5% addition of DMI or arlasolve, pyrrolidone or transcutol, or 1% transkarbam 12. All enhancers in the used concentrations icreased a depot formation in the skin, transkarbam 12 in the lowest concentration. For transdermal in vitro permeation experiments CyA appears to be administered in more lipophilic donor phase. The ideal length of the permeation experiments, it appears time 15 hours.
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Veřejné zakázky a bid rigging
Krejčová, Hana
The Diploma thesis deals with the public procurement issue and the bid rigging. The first part of this thesis is focused theoretically on related legislation of public procurement in the Czech Republic. Herein are in this thesis defined public pro-curements and their types, role of contracting authority and award procedure. The further chapter is devoted to the bid rigging and to its theoretical background. The second part of thesis analyses decisions of the case law of bid rigging, influence of the bid rigging. Furthermore, there are suggested the possible results of detection and prevention of bid rigging.
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The Comparison of Personal Income Tax in the Czech Republic and Republic of Ireland
Obertíková, Sandra ; Krejčová, Hana (referee) ; Kopřiva, Jan (advisor)
The Thesis focuses on a comparison of taxation of individuals in the Czech Republic and in the Republic of Ireland. The Thesis construes a issue of taxation of self-employed and their process of taxation on the examples. In conclusion of this Thesis are tax optimization suggestions for taxpayer. Above that is includes Convention between the Czech Republic and the Republic of Ireland for the avoidance of double taxation and the prevention of fiscal evasion with respect to taxes on income and on capital.
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