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	Adaptive synthesis of functional amphiphilic dendrons for drug nanocarrier assembly Edr, Antonín In this work, an adaptive synthesis of new type of amphiphilic dendrons for nanocarrier purposes will be presented. This methodology was applied in preparation of vast library of substrates. Plný tet: PDF Detailed record
	Modular Synthesis of Dendritic Amphiphiles. Edr, Antonín The synthesis of such structures starts by an attachment of alkyl chain/s R and dendritic wedge/s to the starting molecules. These dendritic wedges are ended by three allyl groups so that various polar groups can be conjugated to the periphery of the wedge by so called thiol-ene click reaction. In addition to the resulting symmetrical structures, a synthesis of their unsymmetrical analogues bearing fluorescent tag on one of its arms (Figure 1) will be presented. Plný tet: PDF Detailed record
	Amphiphilic Dendritic Compounds as Drug Delivery Systems. Edr, Antonín To enable an easy detection of supramolecular objects assembled from 1 or 2, I am currently working on preparation of their unsymmetrical analogues 3 and 4 bearing a fluorescent tag. Final liposomes or micelles will be prepared from mixtures of fluorescent and nonfluorescent analogues.\n Fulltext: content.csg - PDF Plný tet: SKMBT_C22019053108333 - PDF Detailed record

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