|
|
Vzdělanost v zemích EU
Drábková, Natalie
Drábková, N. Education in EU countries. Bachelor thesis. Brno: Mendel University in Brno, 2023. The bachelor's thesis deals with the existence of a relationship between the share of the tertiary educated population and the economic level of the country in selected EU states. In the theoretical part, tertiary education and its impact on the labour market are discussed, as well as academic failure and lifelong learning, and finally, the implementation of the Europe 2020 Strategy and the expansion of Industry 4.0. In the analytical part, the educational structure of representative countries, which were selected on the basis of cluster analysis, is compared. Within the indicator of the university students, elementary characteristics were used to describe the development of the time series of Latvia, Luxembourg, Germany, Spain and the Czech Republic. Finally, a multiple regression was constructed for Germany and Spain. Regression analysis showed that the share of university graduates affects economic performance in Germany. In the other hand, in Spain was no correlation between the given indicators. At the same time, the influence of the unemployment rate on the GDP per inhabitant was proven in this country. At the end of the thesis, it is recommended to politicians to motivate students to study STEM fields, which have a significant impact on economic performance.
|
|
|
Contribution of particular vasoactive systems in the development of chronic kidney disease
Drábková, Natálie ; Vaněčková, Ivana (advisor) ; Vaňourková, Zdeňka (referee)
Chronic kidney disease (CKD) is a life-threating disease which arises as a frequent consequence of diabetes and hypertension. Since it is going on silently, CKD often progresses to the end-stage renal disease. It is therefore necessary to combat this disease especially due to the fact that the world population is growing old. The aim of this work was to determine the contribution of selected vasoactive systems contributing to the maintenance of high blood pressure in the developmental and established phase of CKD. Two models of CKD were used: 5/6 nephrectomy in Ren-2 transgenic rats (TGR) and stenosis of renal artery (2K1C) in Wistar rats. We demonstrated that renin-angiotensin system does not play so important role in blood pressure maintenance in both CKD models. By contrast, a more important role has sympathetic nervous system. During both the developmental and established phase of CKD, vasoconstrictor systems prevail above vasodilator NO-synthase effects. In fact, the role of NO-dependent vasodilation gradually decreased in nephrectomized TGR rats, while it was unchanged in Wistar rats with 2K1C hypertension.
|
|
|
Contribution of particular vasoactive systems in the development of chronic kidney disease
Drábková, Natálie ; Vaněčková, Ivana (advisor) ; Vaňourková, Zdeňka (referee)
Chronic kidney disease (CKD) is a life-threating disease which arises as a frequent consequence of diabetes and hypertension. Since it is going on silently, CKD often progresses to the end-stage renal disease. It is therefore necessary to combat this disease especially due to the fact that the world population is growing old. The aim of this work was to determine the contribution of selected vasoactive systems contributing to the maintenance of high blood pressure in the developmental and established phase of CKD. Two models of CKD were used: 5/6 nephrectomy in Ren-2 transgenic rats (TGR) and stenosis of renal artery (2K1C) in Wistar rats. We demonstrated that renin-angiotensin system does not play so important role in blood pressure maintenance in both CKD models. By contrast, a more important role has sympathetic nervous system. During both the developmental and established phase of CKD, vasoconstrictor systems prevail above vasodilator NO-synthase effects. In fact, the role of NO-dependent vasodilation gradually decreased in nephrectomized TGR rats, while it was unchanged in Wistar rats with 2K1C hypertension.
|
|
|
The role of endothelin system in the treatment of chronic renal failure
Drábková, Natálie ; Vaněčková, Ivana (advisor) ; Vebr, Pavel (referee)
Chronic kidney disease (CKD) is a life-threatening disease arising as a frequent consequence of diabetes and hypertension. Since it is silent for a long time, it often progresses to end-stage renal disease (ESRD). Managing chronic kidney disease, the prevalence of which is sharply increasing in the last decades due to the ageing of the world population, is thus major health problem. Apart from blockers of renin-angiotensin system, which are used as the "golden standard" in the treatment of CKD due to their antihypertensive and renoprotective effects, other strategies are also applied for the management of this disease. A relatively new class of therapeutics - blockers of endothelin system - seems to be very promising in this field.
|
guest ::
RSS feed.