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Vliv cytosolické nukleotidázy cN-IIIB na imunitní odpověď u \kur{Drosophila melanogaster}
 DOLEJŠKOVÁ, Tereza
Adenosine is a key signal molecule of the metabolic switch, a crucial process of metabolic changes in Drosophila melanogaster upon parazitoid wasp infection. However, some components of the adenosine creation pathway have yet to be discovered. We studied a potential convertor of AMP to adenosine in immune response, cN-IIIB, a cytosolic nucleotidase known to accept the methylated RNA cap nucleotide 7-methylguanosine as a substrate and to protect cells against undesired incorporation of this nucleotide into nucleic acids. We suggest this trait can be potentially important in the metabolic switch.
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