National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Histologic analysis of melanoma B16-F10 therapy by agonist of TLRs and fagocyte receptors
DIVOKÁ, Petra
The aim of submited Thesis was to contribute to illustration on effect of TLR and fagocytate receptors in melanoma B16-F10 treatment with mouse model. Currently, a consequence of different ligands of fagocyte receptors and their combination with liposacharide (LPS) was tested. Ligands of fagocytate receptors was used in form enabled inside tumor cells anchoring. It deals with these compounds: f-MLFKK-BAM4000, laminarin-BAM4000, mannan-BAM4000. Gained results confirmed that previously observed huge synergy of LPS (activation of TLR4) and activation of phagocytic receptors by ligands anchored to tumor cells found the clarification in the form of extensive necrotization of tumor mass at the histological level.
Differences of autogeny and anautogeny population of mosquitoes Culex pipiens quinquefasciatus Say
DIVOKÁ, Petra
The aim of submited Thesis was to contribute to illustration on differences in development of female genital organs in autogeny and anautogeny population of mosquito Culex pipiens quinquefasciatus Say. Currently, a consequence of ekdyson agonists was tested for change evoked in the development and fertility this species. Gained results showed that in anautogeny population is process of vitellogenesis depended on blood- feeding. In autogeny population, there is no need to blood- fed during the first gonotrophic cycle. Tested compound indicated vitellogenesis in a sublethal doses then egg-laying was followed. In comparison with that, application of higher doses showed sterilisation effect. Gained results show this compound useful for regulation of mosquitoes population, especially in the area of disease transmitted by them.

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