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The issue of nursing children with percutaneous endoscopic gastronomy
Praksová, Martina ; Pohlová, Andrea (advisor) ; Bláhová, Květa (referee)
Pereutaneous Endoseopie Gastrostomy {further on PEG} has heen peďonned for the first time in USA in June 1979. At tbat time it was recived as a very risky metbod. Fortunatelly it did not last a very long time and this new metbod has ehanged in a ski11ed and very needed aceomplishment. In Czeeh Republie this method appeared later - in 90th years of 20th eentury. But soon it has got in eonseiousniss of doctors and other medical statI. And very promptly beeame a eomponent of tbe programme in all of tbe major hospitals. I am work.ing as an endoseopical nursing sister at tbe gastroenterologieal departmant of tbe pediatrie clinie of FN Motol. At our workplace we are engaged in tbe PEG method since the year 1996. Sinee this time we have introdueed 134 PEG's and have earried out 42 interehanges. The working processes do not significantely methodiealy distinguish at tbe pediatrie and adults patients. Aeeordingly to tbe age and namely to tbe weight of the patient it is necessary to choose the needful instruments {an endoseop and gastronornieal set}. It is possible to introduce tbe PEG sueeessfully into small ehildren. Our smallest pediatrie patient, into which we have introdueed tbe gastronomieal sound was 3 months old girl, witb weight 4 kg. At some of our pediatrie patients we have alredy realized one or more...
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Pathogenetic mechanisms determining the origin and development of a hemolytic-uremic syndrome in children
Karnišová, Lucia ; Bláhová, Květa (advisor) ; Skálová, Sylva (referee) ; Podracká, Ľudmila (referee)
Hemolytic uremic syndrome (HUS) induced by Shiga toxin-producing E. coli (STEC) is the most common causes of acute kidney injury in children. The therapy of the disease is symptomatic and the main factors leading to the development of severe course of a STEC-HUS are still unknown. In our study, we dealt with factors leading to development of a severe course of STEC-HUS in pediatric patients on both the host and pathogen side. Using retrospective analysis of the courses in children in the Czech Republic, we found that the most common cause of STEC-HUS was serotype O26 and HUS most often affected children under 3 years of age. 63,8 % required dialysis and mortality was 8.62 %. On the host side we focused on the relationship between the activation of the alternative complement pathway and the severity of the course of HUS. We found a significant difference in the level of the C3 part of complement in patients who required dialysis and patients for whom dialysis was not necessary. We also a cut-off value for the C3 part of complement and its reduction below 0.825 g / l was associated with the need for dialysis treatment and a higher incidence of extrarenal complications. Based not only on our results, it can be assumed that the therapeutic effect of complement could affect the severity of the disease....
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The issue of nursing children with percutaneous endoscopic gastronomy
Praksová, Martina ; Pohlová, Andrea (advisor) ; Bláhová, Květa (referee)
Pereutaneous Endoseopie Gastrostomy {further on PEG} has heen peďonned for the first time in USA in June 1979. At tbat time it was recived as a very risky metbod. Fortunatelly it did not last a very long time and this new metbod has ehanged in a ski11ed and very needed aceomplishment. In Czeeh Republie this method appeared later - in 90th years of 20th eentury. But soon it has got in eonseiousniss of doctors and other medical statI. And very promptly beeame a eomponent of tbe programme in all of tbe major hospitals. I am work.ing as an endoseopical nursing sister at tbe gastroenterologieal departmant of tbe pediatrie clinie of FN Motol. At our workplace we are engaged in tbe PEG method since the year 1996. Sinee this time we have introdueed 134 PEG's and have earried out 42 interehanges. The working processes do not significantely methodiealy distinguish at tbe pediatrie and adults patients. Aeeordingly to tbe age and namely to tbe weight of the patient it is necessary to choose the needful instruments {an endoseop and gastronornieal set}. It is possible to introduce tbe PEG sueeessfully into small ehildren. Our smallest pediatrie patient, into which we have introdueed tbe gastronomieal sound was 3 months old girl, witb weight 4 kg. At some of our pediatrie patients we have alredy realized one or more...
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