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National Repository of Grey Literature

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DNA Microarrays and Bioinformatics in Biomedical Research Ivánek, Robert ; Forejt, Jiří (advisor) ; Martásek, Pavel (referee) ; Beneš, Ivan (referee) Abstr€gt DNA microanays ť€present a relatively novel tecbnique for qualitative and quartitative analysis of nucleic acids. In various modificďions tbis tecbniqueďows expressionmalysis' comparative genomic Mridizatiotr, micronNe profiling, analysis of geire regulation md deteďon ďpolymorpbism or mutations.In this thesisI presentan overview ďvarious types of microarays and theř applióations in biomedical reserch. I documett their usefulnessful severalprojecb aimedatidentificatioaof diseasecausinggenes(Mucopolysaoetaidosis lII€, ATP syntbasedefieielrcy),at moleculaÍchaae*erizatim ď h'man disws using cell lines (clear cell renal carcinoma,acutemyeloid leukaenia) or meute modďs (meiotic ďlonoiug of unsynapsedcbronatin). My work de'monsbtes that oompetentapplication of microarray techiqge4. bve pobqtiel to speed rrp biomedicď re"searcáod already bocane one of its frrndmental analyticalapproaches. ' t Detailed record

Charakteristika znečištění vnitřního prostředí obytných budov vlivem jednotlivých činností :: porovnání se znečištěním vnějšího prostředí Beneš, Ivan ; Okresní hygienická stanice Teplice Detailed record

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1	Beneš, Ivo

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