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Effect of pharmacotherapy in idiopathic thrombocytopenic purpura (ITP)
BRYCHTA, Jakub
This study focuses on the monitoring of platelet count dynamics during pharmacotherapy in patients with idiopathic thrombocytopenic purpura (ITP) and the comparison of the efficacy of different treatment strategies. To achieve this goal, venous blood samples from patients diagnosed with ITP were analyzed and stored in the anticoagulant K3EDTA. Subsequently, platelet count (PLT) and percentage of immature reticulated platelets (IPF) were quantified using the XN series hematology analyzer from Sysmex. All results were recorded and evaluated in excel software. Subsequently, 3 tables were created from the results and patients were categorized according to the type of treatment. Finally, 5 case reports of patients with ITP were selected. The results of this study provide insights into the effects of pharmacotherapy in patients with ITP and provide insights into the effectiveness of different treatment options. These findings may provide useful information for envisioning the optimal treatment regimen for individual patients with ITP. A better understanding of aspects of this disease may lead to an improved quality of life for patients with ITP. The individual response of patients to treatment is crucial, with the choice of treatment depending on the severity of symptoms and side effects. Mean platelet values differed between the groups of patients without treatment, with first-line and second-line treatment. I also noted that proper treatment can lead to an increase in platelet count. Individual approach to patients and regular monitoring of response to treatment is important. New methods of pharmacotherapy for ITP offer a more targeted treatment effect.

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