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National Repository of Grey Literature

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The efficient synthesis of 2-aryl substituted pyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling Česnek, Michal ; Břehová, Petra ; Dračínský, Martin ; Holý, Antonín ; Janeba, Zlatko A series of novel acyclic nucleoside phosphonates with a built-in 2-arylsubstituted pyrimidine moiety has been prepared using the Liebeskind-Srogl cross-coupling protocol. The reactions of highly functionalised 2-methylsulfanylpyrimidines with various arylboronic acids were studied and optimised. Detailed record

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