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National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Treatment of rheumatoid arthritis
 Šumpichová, Veronika ; Hrdina, Radomír (advisor) ; Herink, Josef (referee)
Summary: Approximately 1% of population around the world is currently suffering of rheumatoid arthritis. It is an autoimmune chronical inflamatory disease that affects joints. However, usually also other tissues or systems are affected. The crucial is an oblique immune process when the body is responding to the unknown factor by creating antibodies and destroying itself. The development of the disease can be affected by combination of genetic predisposition and until now non-indetified agent or agents. Moreover, the general influence on disease have female gender, positive family history, effect of silicium compounds or consumption of more than three cups of coffee a day. Originally used concept of pharmacotherapy was aimed at slow and non-agressive therapy based on serial distribution of anthirheumatic medicines. The treatment was treating the disease symptomatically. However the symptoms have dissapeared, the progress of the disease was not decelerated. The crucial change in the pharmaceutical field of research has appeared in prescribing new medicines and within the change of pharmacotherapeutical style; these changes has been affected by high number of side effects of the previous treatment. Aim: To summarize the latest trends in pharmacotherapy of RA, esspecially in last ten years. Conclusion:...
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