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Investigating novel approaches to linear epitope mapping; biophysical characterization of tau protein and its interactions with anti-tau antibodies
BERANOVÁ, Jana
Intraneuronal filamentous lesions which are characteristic for Alzheimer´s disease, the so called neurofibrillary tangles (NFT´s), are misfolded beta-sheet like aggregates of tau protein. Their presence is closely linked to neurodegeneration and progression of the disease. Tau protein has been investigated as a promising target for therapeutic intervention of AD. Several monoclonal antibodies specific to tau protein were previously identified and recovered from human blood serum. As potential candidates for development of biopharmaceuticals, the anti-tau antibodies and their interactions with tau epitopes are to be investigated in detail. This work aims to develop novel methods for linear epitope mapping and to characterize binding sites of identified anti-tau antibodies on tau protein.
Maternal comfort during spontaneous and induced labour
BERANOVÁ, Jana
Bachelor thesis deals with comfort of a mother-to-be during spontaneous and induced labour. Spontaneous labour has assumed on the basis of natural mechanisms of a woman´s organism and was going on without obstetrician´s interventions. In the opposite we understand with the induced labour an artificial evocation of the womb activity in order to end pregnancy with a vaginal delivery. Comfort is closely connected with the delivery; it is defined as situation of physical, psychic and social well-being or peace. Bibliography distinguishes between a physic and social comfort and an environmental comfort. In the theoretical part of this work is this closer described based on quoted bibliography and newest findings in this field. Further is in detail elaborated the nursing care of women in induced and spontaneous labour and the role of midwives during all delivery phases. The practical part of the thesis is aimed to perception of comfort differences at spontaneous and induced delivery by women during the labour. For this thesis was set only one goal, just to find out exactly the difference in perception of spontaneous and induced delivery by mothers-to be during the delivery. Two research questions were determined. Wording of the first question: "How do women evaluate the difference of pain perception of the womb activity at spontaneous and induced labour?" Second questions pursued differences in the medical procedures: "How do women evaluate the difference in medical procedures in case of a spontaneous and induced delivery?" For processing of this problematic and finding out of the given goal was chosen a quality research. For the data collection was used the technique of half structured interviews. These interviews were later processed with the method of content analysis. The research array were women after labour at the puerperium department of hospital Nemocnice Strakonice, a. s. For the quality research were eight women selected, who have the experience with both types of the labour (spontaneous and induced). Based on these quality research results were reached further described conclusions and answers to research questions. The majority of respondents handled better the spontaneous labour. Only one respondent was more satisfied with the progress of inducted delivery. All approached respondents realized that inconveniencies and pain, which accompany the labour, are inseparable part of the labour action, however there were detected significant differences primarily in experiencing of womb contractions. During the spontaneous delivery expectant mothers reported gradual entrance of contractions, so they could have used to the pain and get ready for it. During the induced delivery was the ache sudden, sharper and permanently intense. The biggest difference in the delivery leading experienced all respondents (without one) in the possibility of free movement, which was possible only during the spontaneous labour. During the induced labour was the motion supposedly restricted by frequent CTG-checks and often repeated vaginal screening. Further they could have drunk and eaten during the spontaneous delivery. They have used more non-pharmacologic relief methods by the spontaneous delivery too - like relief positions, aromatherapy, gymnastic ball, massages, shower etc. During the induced delivery they have already asked for pharmacologic methods. An effort of the expert public, mostly of the midwife, is to create the best possible level of comfort to women in labour, so they are satisfied with the labour progress and manage the own delivery best possibly. This bachelor thesis can serve as information material for pregnant women, who are actively getting ready for coming labour. Even future midwives, who prepare their selves for this job can use it, alternatively is it aimed for special midwives ("duly") and other persons attending the delivery.
Audiovisual publicity matter as component public relations of infant school.
BERANOVÁ, Jana
In my Bachelor´s Report I try to introduce the area of ``Public relations{\crqq} (PR) and relate disciplines which are closely connected with this area/discipline. The different questions related to PR are described in every single part of this report. Closer view is devoted to one of PR tool which is an audiovisual presentation. In practical part of this report I concentrate on concrete function of kindergartens and on the forms of presentations which are used by kindergartens. The screenplay for audiovisual presentation of kindergarten is the output of this part. It includes the creating of DVD presentation of concrete kindergarten.

National Repository of Grey Literature : 50 records found   beginprevious47 - 50  jump to record:
See also: similar author names
6 BERANOVÁ, Jitka
1 Beranová, J.
16 Beranová, Jana
2 Beranová, Jana,
4 Beranová, Jaroslava
6 Beranová, Jitka
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