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Transjugular intrahepatic portosystemic shunt: long-term patency in patients with hypercoagulation disorder
Renc, Ondřej ; Krajina, Antonín (advisor) ; Válek, Vlastimil (referee) ; Lata, Jan (referee)
Transjugular intrahepatic portosystemic shunt: long-term patency in patients with hypercoagulation disorder Aim: To retrospectively evaluate the efficacy and long-term patency of transjugular intrahepatic portosystemic shunt (TIPS) in patients with hepatic vein thrombosis due to hypercoagulation disorder. Material and method: In years 1992 - 2011, totally 38 patients with hepatic vein thrombosis resistant to medical therapy underwent TIPS creation in our department. We treated 9 males and 29 females, age 13 - 76 years (median 33 years), 6 patients were children. The underlying thrombophilic state was confirmed in 84,2 % of treated patients. The Budd-Chiari syndrome was acute in 6, subacute in 18 and chronic in 14 cases. Ascites was indication for TIPS in 31 patients, liver failure in 5 and gastrointestinal bleeding in 2 persons. All the procedures were performed in analgosedation or under general anestesia using standard technique. In 17 patients, we implanted non-covered stent or combination of non-covered and covered stents during TIPS creation, in the other 21 patients only the TIPS dedicated covered stents had been used. TIPS patency during follow-up after the procedure was based on regular ultrasonographic, clinical and laboratory examinations. In case of shunt dysfunction, a reintervention was...
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