University of South Bohemia in České Budějovice

University of South Bohemia in České Budějovice 45,085 records found  beginprevious21 - 30nextend  jump to record: Search took 0.00 seconds. 
THE SECRETS ENCODED IN THE DRAFT GENOME OF Lentzea sp. STRAIN BCCO 10_0061 ISOLATED FROM RECLAIMED MINE HEAPS
KELLER, Moritz
Many Actinobacteria including Lentzea have been found to produce medically viable compounds like antibiotics and antitumor agents. This thesis deals with genome sequencing of Lentzea sp. BCCO 10_0061, assembly, annotation and evaluation of the potential for secondary metabolite production, as well as phylogenetic classification and creation of a metabolic profile.
Functional analysis of cryoprotectant system in Chymomyza costata
GRGAC, Robert
In this study, employing an integrated approach that involves transcriptomics, metabolomics, and other techniques, we aimed to understand the mechanistic roles of the cryoprotective system underlying extreme freeze tolerance in the larvae of the drosophilid fly, Chymomyza costata. Metabolomics unveiled the complex composition of the seasonally accumulated larval innate mixture of putative cryoprotectants. This mixture was predominantly composed of proline and trehalose, supplemented by minor components (glutamine, asparagine, betaine, sarcosine, glycerophospho-choline, and ethanolamine). We identified food ingestion as a significant source for the direct assimilation of amino compounds, while glycogen and phospholipids served as the primary internal sources for the biosynthesis of other cryoprotectants. The utilization of MALDI-MSI to observe cryoprotectants revealed distinct behaviors of proline and trehalose during ecologically relevant, gradual inoculative extracellular freezing of larvae. Trehalose exhibited accumulation in partially dehydrated hemolymph, inducing a transition to the amorphous glass phase. On the other hand, proline migrated to the boundary between extracellular ice and dehydrated hemolymph and tissues, forming a layer of dense viscoelastic liquid. Finally, through a combination of in vivo and in vitro assays, we found that cell membranes are likely targets of freezing injury, while their integrity is sustained by accumulated small cryoprotective molecules and proteins in cold-acclimated C. costata larvae. Contrary to our expectations, our assays did not provide support for the hypothesis that proteins (soluble enzymes) require in vivo stabilization through the accumulation of cryoprotectants.
Efficient communication of SMEs with geographically limited target groups
ENZ, Christian
The subject of this doctoral thesis is the communication behaviour of SMEs with a geographically defined business area. Two research objectives are pursued. Firstly, it is to be clarified whether a communication mix adapted to regional economic regions can be developed into a competitive advantage for SMEs compared to nationally or globally operating corporations. Secondly, if this is the case, a method will be developed that allows SMEs to create a more effective communication mix without particular in-house expertise or a marketing agency to be commissioned. To achieve the research objective, the behaviour of companies and consumers in the regions of Prague, South Bohemia, Nuremberg and Middle Franconia is first analysed. Based on a large-scale survey, a statistically significant dependence of corporate communication on the company's location can be identified. According to Cohen, there are also medium and firm regional dependencies in media use on the part of consumers. These dependencies provide a positive answer to the first research question. There are regional differences in media utilisation - both among SMEs and recipients. In line with Porter's competition theory, this offers optimisation potential and even the opportunity to gain a competitive advantage over nationally or internationally active market players. A further aim of the research was to develop a metric enabling decision-makers in SMEs to evaluate the available communication options without in-depth marketing expertise. As part of a literature review, the FLOW distance metric, which has primarily been used in software development to date, was identified as a suitable instrument and modified so that this metric can be used to evaluate marketing communication channels. The FLOW distance is a mathematical value quantifying an imaginary distance between the communicating company and the recipient. If the FLOW value is high, a message must travel a long way from the sender to the recipient - the communication channel, therefore, has a low level of effectiveness. The lower the FLOW value, the more efficient the means of communication. The determination of the FLOW distance is based on an easy-to-use formula - which is why the second research objective is also achieved. The significance of the FLOW distance is achieved because it takes into account the perceived intensity on the customer side. For this purpose, a consumer survey in the four target regions determines the perceived influence per communication channel. The suitability of a communication channel is also taken into account. To this end, the author quantifies the suitability of individual communication channels by employing an expert survey. In the process, 13 marketing communication channels are analysed as part of a descriptive analysis. The aspects of costs, time expenditure, personnel intensity, necessary frequency and required expertise are considered.
Rozvoj kompetencí k podnikavosti a řízení MSP
SLABOVÁ, Michaela
The aim is to select and identify key competencies that help develop students' entrepreneurship and to evaluate the importance of the selected competencies for entrepreneurship from the perspective of SME entrepreneurs and students of economics. Furthermore, the goal is to evaluate the appropriateness of the selected teaching methods from the students' point of view and to determine the contribution of the selected management simulator Gretail International to the development of key competencies for business.
Nevhodné chování žáka ve výuce
BAROŠOVÁ, Jitka
Práce je zaměřená na nevhodné chování žáků ve výuce, základní taxonomii nevhodného chování, reakce na prostředí, podněty a osobu učitele a postoj učitele k nevhodnému chování žáka a jeho řešení. Práce je koncipována jako kvantitativní výzkum pomocí dotazníkového šetření u učitelů.
Projektové vyučování - případové studie
ŠEBKOVÁ, Ludmila
This final paper examines the use of project-based learning methods in teaching civics and economics in high school. The theoretical part defines the attributes and application of the project as a teaching tool and describes the specific position of case studies in this area. The practical part is based on the application of these methods in teaching. The work aims to evaluate the benefits that project-based teaching methods bring to secondary school students and to reveal the potential risks that educators have to face when applying them.
Analýza volnočasových pohybových aktivit vybraného vzorku žáků na různých typech škol
DRBOHLAV, Jakub
Skloubení volného času a pohybových aktivit, které provádíme v mládí, určuje náš budoucí postoj ke sportu a pohybu obecně. Tato závěrečná práce se zaměřuje na vybraný vzorek žáků na různých typech škol. Zjistíme, jakému typu pohybových aktivit dávají žáci přednost. Stejně tak si utvoříme náhled do četnosti a různorodosti pohybových aktivit dnešní mládeže. Analýzu provedeme standardizovaným dotazníkovým šetřením. Následně se data vyhodnotí a porovnají.
Třída jako sociální skupina
PEŠKOVÁ, Klára
Práce se zabývá školní třídou jako sociální skupinou. V teoretické části jsou popsány základní charakteristiky sociální skupiny s důrazem na znaky malé sociální skupiny a její utváření, resp. zaměřuje se na specifický typ - školní třídu. Praktická část zkoumá začlenění dětí z Ukrajiny do třídního kolektivu a nabízí i vhodné postupy.
Inovace ve výuce
VRONKOVÁ OŽANOVÁ, Monika
This thesis with the topic of Innovation in Teaching. In the theoretical part I define the concepts of the curriculum of Czech education and planned innovations in education by the state, I also define the concept of educational innovation and teaching methods. The aim is to find out what possibilities teachers have to innovate their teaching.

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