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National Repository of Grey Literature

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Electrochemical detection of prion proteins Chepizhko, Veronika This study is focused on different methods that allow to detect prion proteins (infectious proteins, causing a group of fatal neurogenerative diseases, affecting humans or other animals). In this research mice antigen and antibody, that are not infectious as prion proteins, were used as a model. The main research is based on electrochemical protein detection, using classical three-electrode impedance method. As a result, efficiency of this method was proofed, and appropriate concentration of antibody and antigen was found. This is important because knowing an appropriate concentration that is used in this method allows to get precise results, in the meantime, to use chemicals rationally. Detailed record

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