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Cold perception and cold receptors
Kužílková, Johana Abigail ; Žurmanová, Jitka (advisor) ; Ptáková, Alexandra (referee)
Cold perception is a crucial sensory phenomenon for the survival of most organisms. It facilitates the selection of appropriate thermoregulatory responses necessary for maintaining organismal integrity and aids in spatial orientation. However, the mechanisms underlying cold perception remain incompletely understood. Central to this process are cold receptors, proteins capable of depolarizing cells and eliciting action potentials in response to cold stimuli. This study aims to review and understand the current literature on two key aspects related to cold perception. Firstly, it seeks to elucidate how contemporary knowledge explains an organism's ability to discern a wide range of cold temperatures. Secondly, it endeavours to explore the identified or hypothesized cold receptors and the extent of our knowledge regarding their functional role in the perception of cold. Key words: Cold perception, cold activated receptors, TRPM8, TRPA1, TRPC5
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