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National Repository of Grey Literature

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The role of laypersons in the ethics committee for assessment of clinical research in the Czech Republic Kašková, Petra ; Doskočil, Ondřej (advisor) ; Šimek, Jiří (referee) The clinical research is an indispensable part of the progress in medicine, therapy, but also in diagnosis. It is really necessary to realize the complexity of the ethical issues to explore the unknown on a human body. When ethically considerating it is necessary to come from the respect and protection of the dignity and human rights who take part in the clinical trials and these interests should always prioritize over the scientific and social interests. A crucial role in the clinical research regulation has the ethics committee. Members of the ethics committees shall have some professional behaviour, some experience and moral credit to be able to review clinical trials. Just members of the ethics committes can answer the queries regarding the mission and the purpose of the ethics committees work at all. Ethics committees have different representation in different countries. Ethics committees in the Czech Republic are composed of the experts - doctors and the laypersons, so lay people representing especially patients. In the theoretical section we present the history of the clinical research and impact of the research ethics committee. We present informed consent as a key document for patients entering the clinical trials. We also describe the activities and legislation of the ethics committee and... Detailed record

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