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Acute effect of head down tilt on blood pressure and haert rate
Tolar, Jan ; Radvanský, Jiří (advisor) ; Procházka, Michal (referee)
Whereas the effects of a long-term activity of head-down tilt (HDT) in the angle between 3ř and 12ř were examined in details in cosmic medicine as the model of a state of weightlessness, literature concerning effect of HDT on cardiovascular control in the angle over 30ř is scarce. The aim of the thesis is to examine acute reaction of systolic, diastolic, mean arterial blood pressure and heart rate during three minutes of 30ř, 50ř and 70ř HDT, realized on a tilt (inversion) table with fixed legs. For the combination of HDT and head-up tilt (HUT), the following protocol was chosen: 5 minutes lying in a horizontal position (HOR), 3 minutes of 70ř HUT, 3 minutes of 30ř HDT, 3 minutes of HOR, 3 minutes of 50ř HDT, 3 minutes HOR, 3 minutes of 70ř HDT, 3 minutes HOR and 3 minutes of 70ř HUT. A non-invasive continuous Peňáz method, using Finapres Ohmeda, was used to monitor beat-by-beat blood pressure and heart rate. Blood pressure was also measured by sphygmomanometer each minute for calibration. In the angle of 30ř HDT, there was a significant decline of heart frequency (p < 0,01). During the 50ř HDT, there was a significant rise of systolic blood pressure in the third minute, of diastolic and mean arterial pressure each minute and the heart rate dropped significantly (all p < 0.05). In the 70ř HDT,...

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