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Role polymorfonukleárních leukocytů během zánětlivé odpovědi mléčné žlázy skotu
Steinerová, Michala
The mammary gland is an important production body in dairy cattle breeding. Due to breeding and hybridization programs it reached a position of highly functional exploitation body, which threatens its integrity and homeostasis. The most common health problem of dairy cows is mastitis. As a result, during the evolution, one of the most important defence mechanisms was created, an inflammatory response. It is divided into two stages: stage of initiation and resolution. In both of these stages, polymorphonuclear leukocytes (PMN) play very important role. They migrate from the bloodstream, adhere to the capillary walls, they get through them by diapedesis, and travel to the site of inflammation. There the elimination of pathogens through phagocytosis takes place. Then the damaged tissue is repaired. PMNs undergo apoptosis and they are phagocytosed by macrophages. Therefore, the aim of this work was to study recommended literature and to compile it into the literary research, which would summarize all findings about PMN's role during the inflammatory response of bovine mammary gland.
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